Treatment Resistant Depression: A Roadmap for Effective Care - Tapa blanda

"Dr. Greden and colleagues have written a road map for treatment resistant depression that has immediate appeal for the general practitioner and mood specialist alike. The case vignettes with evidenced based reviews and clinical pearls in mood disorders with emphasis on areas often underdeveloped (young adults, dual diagnosis, late life) make "Treatment Resistant Depression: A Roadmap for Effective Care" a great resource for my practice and my patients."-- "Mark A. Frye, M.D., Professor of Psychiatry, Director, Integrated Mood Group, Mayo Clinic, Department of Psychiatry " "Many of the case vignettes represent some of the patients who have been referred to me because they suffer from treatment resistant depression. Several chapters cover patient populations that are often underrepresented in the current literature. While I would recommend reading the first chapter before the other chapters, any chapter can be read in a relatively short time to get clear and concise information on a specific case. The well-written concluding chapter on genetics updates readers on the current research in this exciting area, which has great potential for use in treatment resistant depression. While complementary and alternative treatments are interspersed throughout the book, a specific chapter that reviews all of the potential treatment options that patients are pursuing outside of the traditional medical model, and the research findings behind those treatments, would have been a helpful addition."-- "Aaron Plattner, M.D., DOODY'S PUBLISHERS' CLUB", "July 2011"

As many as 35-40% of patients afflicted with Major Depressive Disorder (MDD) are treatment resistant, a situation that places a massive emotional and financial burden on society and challenges the mental health profession to develop new treatment paradigms and practices. Even the most astute clinicians can be frustrated when treatment options fail to be effective or work for only a brief time, leaving them to wonder what course to pursue next. Treatment Resistant Depression: A Roadmap for Effective Care gives clinicians and their patients what they need most desperately: a sequence of steps that reflect state-of-the-art diagnostic procedures and integrates all evidence-based treatment modalities -- in short, a roadmap to wellness and recovery. Based primarily on the experiences of the authors, all of whom are leading researchers and/or clinicians in Treatment Resistant Depression and affiliated with the University of Michigan Comprehensive Depression Center, the book also draws upon the clinical research advances and treatment innovations of programs around the world. Although the book's step-by-step organization is clear and easy to follow, its coverage, scope, and level of sophistication are anything but simplified. This book Is comprehensive, addressing treatment options, including psychopharmacotherapy, psychotherapy, neuromodulation (ECT, transcranial magnetic stimulation, deep brain stimulation, vagus nerve stimulation), exercise, nutrition, self-management approaches to enhance adherence, behavioral sleep programs, and others Addresses treatment resistant depression across the lifespan, reflecting the diverse demographics of depression, which knows no age, gender, or socioeconomic status Emphasizes the authors' commitment to early intervention and provides techniques for identifying young people who are at risk for developing depression or already expressing symptoms of the disease Recognizes the chronicity of depression, rather than focusing on only the acute stage, and in this way allows for more effective treatment over the patient's lifetime Introduces self-management as playing a critical role in the patient's prognosis, engagement, adherence to clinical steps that help maintain recovery, and self-esteem Promotes the development of new, personalized, and predictive biomarkers to target treatment more effectively. Designed to be useful across disciplines and treatment modalities, the book includes a multitude of tables, graphs, and learning aids that will benefit students, instructors, and clinicians. At the same time, the book promises to be a valuable resource for patients and their families, since Treatment Resistant Depression is both difficult to live with and little understood. No other book offers so much practical guidance, sound research and hope.