Functional Selectivity of G Protein-Coupled Receptor Ligands: New Opportunities for Drug Discovery (The Receptors) - Tapa blanda

From the reviews:

“This book presents the current status of knowledge about ligand-specific intracellular signaling. ... This book will be of greatest interest and utility to scientists actively involved in research into G protein-coupled receptors or drug discovery. ... This is a ... thorough, and detailed assessment of the current state of knowledge and recent developments in the field of G protein-coupled receptor function, signaling, and pharmacology.” (Beth Levant, Doody’s Review Service, December, 2009)

“Gives a comprehensive overview on all aspects of the functional selectivity concept of GPCR ligands ... . It will help to generate more awareness for a key topic within the research community. ... the volume at hand is of great educational benefit. ... In general, the volume under review can be considered an excellent book ... . can be an excellent companion for researchers just jumping into the field of GPCR agonist research, as well as for the expert scientist in the field.” (Christoph Boss, ChemMedChem, Vol. 5, 2010)

In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.