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Tropomyosin is one of the two core components of the actin filament and is involved in regulating most if not all functions of these filaments. This book covers all aspects of tropomyosin biology, from gene structure to their role in cell function and disease.
PETER GUNNING, PhD, is Head of the Oncology Research Unit, Department of Pharmacology, School of Medical Sciences, at the University of New South Wales located in Sydney, Australia. The primary focus of his research is the regulation of cell and tissue architecture and its modification in cancer. He is a member of numerous professional organisations and has served on the Boards of the NSW Cancer Council and Bio-Link Partners and as Chairman of the NSW Cancer Council and NSW Cancer Institute Research Committees. Peter received his academic degrees from Monash University, Melbourne, Australia.
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- EditorialSpringer
- Año de publicación2010
- ISBN 10 1441927603
- ISBN 13 9781441927606
- EncuadernaciónTapa blanda
- Número de páginas324
- EditorGunning Peter
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Tropomyosin (Advances in Experimental Medicine and Biology) [Paperback ]
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Tropomyosin (Advances in Experimental Medicine and Biology, 644)
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Tropomyosin
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Descripción Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. PETER GUNNING, PhD, is Head of the Oncology Research Unit, Department of Pharmacology, School of Medical Sciences, at the University of New South Wales located in Sydney, Australia. The primary focus of his research is the regulation of cell and tissue a. Nº de ref. del artículo: 4173252
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Descripción Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - A recent review of one of my grant applications commented on the 'rediscovery of tropomyosin'. I was tempted to write back in my rebuttal to the reviewer that I didn't realise it had been lost. Uncharacteristic maturity prevailed and I resisted the temptation, but I was struck by the underlying observation that research on the str- ture and function of tropomyosin has been somewhat invisible, particularly in terms of the cytoskeleton isoforms. So, how can it be that one of the two major components of the actin filament has been so thoroughly overlooked I suspect that the answer is disappointingly pedestrian. Whereas the biochemistry of the 1980s revealed the potential of tropomyosin isoforms to diversify the function of actin filaments, the subsequent disenchantment with isoform biology in general in the 1990s inhibited growth of this field. With the development of more sophisticated experimental - proaches we are now seeing a growing realisation of the importance of tropomyosin in regulating actin filaments beyond its pivotal role in muscle contraction. The opportunity to edit this book came at a time when we had written several reviews on different aspects of tropomyosin function and I had just finished the background reading for a comprehensive review of tropomyosin biology. I realised that the field was simply beyond the capacity of any one person to do the field j- tice. Nº de ref. del artículo: 9781441927606
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Descripción Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A recent review of one of my grant applications commented on the 'rediscovery of tropomyosin'. I was tempted to write back in my rebuttal to the reviewer that I didn't realise it had been lost. Uncharacteristic maturity prevailed and I resisted the temptation, but I was struck by the underlying observation that research on the str- ture and function of tropomyosin has been somewhat invisible, particularly in terms of the cytoskeleton isoforms. So, how can it be that one of the two major components of the actin filament has been so thoroughly overlooked I suspect that the answer is disappointingly pedestrian. Whereas the biochemistry of the 1980s revealed the potential of tropomyosin isoforms to diversify the function of actin filaments, the subsequent disenchantment with isoform biology in general in the 1990s inhibited growth of this field. With the development of more sophisticated experimental - proaches we are now seeing a growing realisation of the importance of tropomyosin in regulating actin filaments beyond its pivotal role in muscle contraction. The opportunity to edit this book came at a time when we had written several reviews on different aspects of tropomyosin function and I had just finished the background reading for a comprehensive review of tropomyosin biology. I realised that the field was simply beyond the capacity of any one person to do the field j- tice. 324 pp. Englisch. Nº de ref. del artículo: 9781441927606
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Descripción Condición: New. Tropomyosin is one of the two core components of the actin filament and is involved in regulating most if not all functions of these filaments. This book covers all aspects of tropomyosin biology, from gene structure to their role in cell function and disease. Editor(s): Gunning, Peter. Series: Advances in Experimental Medicine and Biology. Num Pages: 304 pages, 80 black & white illustrations, 8 colour illustrations, 8 black & white tables, biography. BIC Classification: MBGR. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 17. Weight in Grams: 618. . 2010. Softcover reprint of hardcover 1st ed. 2008. paperback. . . . . Nº de ref. del artículo: V9781441927606
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Descripción Condición: New. Tropomyosin is one of the two core components of the actin filament and is involved in regulating most if not all functions of these filaments. This book covers all aspects of tropomyosin biology, from gene structure to their role in cell function and disease. Editor(s): Gunning, Peter. Series: Advances in Experimental Medicine and Biology. Num Pages: 304 pages, 80 black & white illustrations, 8 colour illustrations, 8 black & white tables, biography. BIC Classification: MBGR. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 17. Weight in Grams: 618. . 2010. Softcover reprint of hardcover 1st ed. 2008. paperback. . . . . Books ship from the US and Ireland. Nº de ref. del artículo: V9781441927606
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