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Chapters: Plasma Source, Matrix-Assisted Laser Desorption/ionization, Electrospray Ionization, Dart Ion Source, Electric Glow Discharge, Soft Laser Desorption, Chemical Ionization, Electron Cyclotron Resonance, Desorption Electrospray Ionization, Electron Ionization, Surface-Enhanced Laser Desorption/ionization, Matrix-Assisted Laser Desorption Electrospray Ionization, Fast Atom Bombardment, Field Desorption, Thermal Ionization, Sonic Spray Ionization, Thermospray, Inductively Coupled Plasma, Atmospheric Pressure Chemical Ionization, Electron-capture Mass Spectrometry, Arc-Ecris, Penning Ionization, Ion Cyclotron Resonance, Spark Ionization, Probe Electrospray Ionization, Associative Ionization, Duoplasmatron, Chemi-Ionization, Electron Capture Ionization, Charge-Exchange Ionization. Source: Wikipedia. Pages: 114. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization technique used in mass spectrometry, allowing the analysis of biomolecules (biopolymers such as proteins, peptides and sugars) and large organic molecules (such as polymers, dendrimers and other macromolecules), which tend to be fragile and fragment when ionized by more conventional ionization methods. It is most similar in character to electrospray ionization both in relative softness and the ions produced (although it causes many fewer multiply charged ions). The ionization is triggered by a laser beam (normally a nitrogen laser). A matrix is used to protect the biomolecule from being destroyed by direct laser beam and to facilitate vaporization and ionization. The matrix consists of crystallized molecules, of which the three most commonly used are 3,5-dimethoxy-4-hydroxycinnamic acid (sinapinic acid), -cyano-4-hydroxycinnamic acid (alpha-cyano or alpha-matr...More: http://booksllc.net/?id=2190535
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