This is a unique resource for guiding the analysis of oligonucleotide-based drug products. No other single source provides such a comprehensive overview of the necessary analytical techniques that assess the qualitative characteristics of oligonucleotides intended for pharmaceutical use.
―Rachel R Chennault, Ph.D.(American College of Clinical Pharmacy), in Doody's Notes
Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use.
Topics discussed include:
This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.
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Descripción Condición: New. Editor(s): Bonilla, Jose V.; Srivatsa, G. Susan. Num Pages: 511 pages, 266 black & white illustrations, 76 black & white tables. BIC Classification: MBGR; PNF; PSD; TCB. Category: (G) General (US: Trade); (U) Tertiary Education (US: College). Dimension: 176 x 246 x 38. Weight in Grams: 892. . 2016. Paperback. . . . . Books ship from the US and Ireland. Nº de ref. del artículo: V9781138198456