Functional Neural Transplantation III: Primary and Stem Cell Therapies for Brain Repair, Part II: Volume 201 (Progress in Brain Research) - Tapa dura

This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

• Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
• Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
• All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Dunnett is a behavioural neuroscientist who started a lifelong collaboration with the Björklund team in 1979 to explore the functional consequences of cell transplantation method in animal models of neurodegenerative disease, in particular involving cell replacement and repair of the basal ganglia. He has developed models and novel methods of motor and cognitive assessment to apply behavioural analysis not simply to assess functional efficacy of implanted cells, but as a tool to study the mechanisms of cell integration, circuit reconstruction and functional repair. In parallel his laboratory originated the first UK trial of cell transplantation in Huntington’s disease, and provides the source of clinical grade cells for further ongoing trials in Parkinson’s disease.