Metastatic Cell: Behaviour and Biochemistry - Tapa dura

Graduate students who acquire it as a supplemental text will find much to enjoy, ponder and use. - Bioscience; Better view of the current science - Cancer Cells; Clive Evans has succeeded in bringing together in an eminently readable manner the threads of a complex, difficult and rapidly expanding field. ...The clarity of style and wit of the author...immediately captures the attention of the prospective reader. ... This book will fulfill the need of an enormous number of people working in the area of tumour biology for it brings together a thorough synthesis of the recent literature in the field. FEBs Lett.313,323

The normally functioning cell has controls which prevent it proliferating and invading regions of the body from which it is normally excluded. Under certain conditions, the normal rules breakdown and cell proliferation and migration, or metastasis, leads to the formation of tumours. The metastatic behaviour of malignant tumour cells is responsible for the majority of cancer deaths. This book deals with the behaviour and biochemistry of errant cells, a subject that is at the forefront of current reserch in cellular and molecular biology, providing general and specialized information on cell adhesion and mobility in the metastatic process, the behaviour of the cells involved and how they differ from normal cells. Whilst not intended to be all-encompassing, this book provides a general background to the metastatic cell, describing the current status of knowledge about its genotype and phenotype and discussing aspects of its behaviour which are thought to be crucial in the metastatic response. Possible future directions for research and ways in which metastasis might be controlled are also covered. The book aims to give senior biological, medical and veterinary students an understanding of the metastatic cell and is a synthesis of current research for more advanced workers.