The Archives of Internal Medicine, Vol. 16: October 15, 1915 (Classic Reprint) - Tapa dura

Excerpt from The Archives of Internal Medicine, Vol. 16: October 15, 1915

It is not within the scope of this paper to include more than a brief summary of the literature. A complete bibliography of those publica tions which specifically consider the relation between syphilis and Raynaud's disease has been added for those more fully interested. Raynaud's disease is uncommon, yet its occurrence is not so extremelv infrequent as to relegate it to the category of medical rarities. Cassirer saw 56 cases, and including a careful review of the literature up to 1911, has gathered together over 300 unquestioned instances of the disease. Coming now to the group of cases in which an hereditary or acquired lues is present, we find a considerable discrepancy in the figures published. Monro would allow only per cent, while Cas tellino and Cardi find 22 cases of syphilis in 306 cases of Raynaud's disease. Probably the proportion is still higher. The appended 54 references contain more than 22 cases. Perhaps 10 per cent. Will not be too high an estimate.

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