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'This is a work of real scholarship, a critical account of a huge swathe of work The sharp focus on one type of damage, the excellent writing style and the well argued, personal perspective of the author contrive to keep the reader going.' - Nature
'The book represents a substantial effort and documents the broad and deep insight that Vijg has into the field of aging. It should greatly stimulate interest and the entry of promising new scientists into the field and will help heighten the profile and importance of aging research in general.' - Nature Genetics
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'The book represents a substantial effort and documents the broad and deep insight that Vijg has into the field of aging. It should greatly stimulate interest and the entry of promising new scientists into the field and will help heighten the profile and importance of aging research in general.' - Nature Genetics
Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change.
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- EditorialOxford University Press, USA
- Año de publicación2007
- ISBN 10 0198569238
- ISBN 13 9780198569237
- EncuadernaciónTapa blanda
- Número de edición1
- Número de páginas384
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Aging of the Genome The Dual Role of DNA in Life and Death
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Aging of the Genome: The Dual Role of DNA in Life and Death
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Aging of the Genome: The Dual Role of DNA in Life and Death
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Descripción Paperback. Condición: new. Paperback. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recentadvances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleteriouseffects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. This book reviews the concept of genomic instability. It provides underlying biology of aging, driven by continuing demographic change. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Nº de ref. del artículo: 9780198569237
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Aging of the Genome The Dual Role of DNA in Life and Death
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(2007)
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ISBN 13: 9780198569237
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ISBN 13: 9780198569237
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Descripción Paperback. Condición: new. Paperback. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recentadvances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleteriouseffects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases. Moreover, there is a growing public recognition of the imperative of understanding more about the underlying biology of aging, driven by continuing demographic change. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. This book reviews the concept of genomic instability. It provides underlying biology of aging, driven by continuing demographic change. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. Nº de ref. del artículo: 9780198569237
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Aging of the Genome
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Descripción Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. This book reviews the concept of genomic instability. It provides underlying biology of aging, driven by continuing demographic change.Aging . Nº de ref. del artículo: 446842744
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AGING OF THE GENOME: THE DUAL RO
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