Duchenne Muscular Dystrophy (Monographs on Medical Genetics)

Duchenne muscular dystrophy is a common genetic disorder affecting primarily young males. The author draws on his own studies of treating more than 200 patients and gives a critical account of what is now known about a disease that has been the subject of much clinical research in the last decade. The book discusses the identification and isolation of the locus of the responsible gene, its unexpected size and complexity and the characterization of the related protein, dystrophin, which is a component of skeletal muscle.