The Peripheral Actions of 5-Hydroxytryptamine - Tapa dura

The properties of 5-hydroxytryptamine (5-HT or serotonin) and its physiological significance have been the subject of great interest due mainly to the advent of a number of new drug tools, several of which show therapeutic promise. This book describes the major advances in this important area, specifically with respect to the actions of 5-HT on the periphery. The scope is broad, covering 5-HT synthesis and catabolism, its receptors and their second messenger transduction systems, and all major aspects of the functional responses to 5-HT in peripheral tissues. Emphasis has been placed on the significance of major developments in the treatment of cardiovascular, gastrointestinal and peripheral vascular disease. The book should be of interest to pharmacologists, neuropharmacologists, neurochemists, neurobiologists and physiologists.