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“It is a remarkably concise exposition of the use of MDPs in a pharmaceutical setting; as such, the book’s audience is the intersection of researchers and students with a sophisticated mathematical background and professionals in the pharmaceutical industry. ... the book is a very sophisticated treatise on MDP models for managing response-adaptive clinical trials and both mathematicians and pharmaceutical professionals would appreciate it.” (James Smith, Interfaces, Vol. 45 (4), July–August, 2015)
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Descripción Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences. 120 pp. Englisch. Nº de ref. del artículo: 9783658083434
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Descripción Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences. Nº de ref. del artículo: 9783658083434
Descripción Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Publication in the field of natural sciencesThomas Ondra obtained his Master of Science degree in mathematics at University of Vienna. He is a research assistant and PhD student at the Section for Medical Statistics of Medical University of Vienna.I. Nº de ref. del artículo: 5123867