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Here, documentations for the established MAK values (maximum workplace concentrations) or selected occupational toxicants such as aniline, chloroform, or methacrylic acid are provided. The documentations include an authoritative review of the available toxicological studies and data. For every substance, toxic effects, mechanisms and modes of action, toxicogenetics and metabolism, effects in man and animals are described. The carcinogenic, germ-cell mutagenic, sensitizing or skin-resorptive effects as well as their toxicity to the reproductive system are evaluated. Basic physic-chemical data are provided as well. The documentations are thus not only essential for the application of MAK values but provide a concise toxicological overview for each substance.
The documentations are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria. MAK values set the standards for legal regulations in many countries of the world, e.g. they are the basis for at least 30% of the threshold limits valid in the European Union and they are also frequently referred to in Asia.
The complete MAK-Collection is also available online: www.mak-collection.com
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