Mémoire sur la Fermentation appelée lactique, pp. 404-418 in Annales de Chimie et de Physique, Troisième Série, Tome 52, April, 1858. A MILESTONE IN BIOCHEMISTRY

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First edition, complete journal issue in original printed wrappers, of this landmark paper, "often considered the beginning of bacteriology as a modern science, [which constitutes] the first demonstration of the connection between a specific fermentation and the activity of a specific microorganism" (Garrison & Morton). "In this epochal paper [Pasteur] first published his research on lactic fermentation . . . A great milestone in biochemistry" (Neville II, p. 274). "Pasteur's first paper on fermentation contains most of the central theoretical and methodological features of his biological theory of fermentation, in particular the concept of fermentation as a product of the growth of yeast, the idea that air is a source of microscopic yeasts and other micro-organisms, and the notion of specificity, in which each fermentation could be traced to a specific micro-organism" (Dibner). "Pasteur's concept of fermentation as a biological process challenged the chemical theory of fermentation put forth by Liebig, which Pasteur was able to disprove with his experiments on alcoholic and acetic fermentation" (Norman). Dibner 198, Garrison-Morton 2472 and Horblit 82 (abridged version); Norman 1653 (offprint). 8vo, pp. 365-512, (uncut and partially unopened, a few small spots of damp). Original printed wrappers (contemporary signature on front wrapper, a few small chips from wrappers, spine rubbed). N° de ref. del artículo ABE-1595586604794

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