springer us apr 1996 (61 resultados)

Taschenbuch. Condición: Neu. Neuware -'.a story of great mathematicians and their achievements, of practical successes and failures, and of human perfidy and generosity.this is one of the still too rare occasions in which mathematicians are shown as frail, flesh-and-blood creatures.a very worthwhile book.' -CHOICESpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Buch. Condición: Neu. Neuware -Permutation Groups form one of the oldest parts of group theory. Through the ubiquity of group actions and the concrete representations which they afford, both finite and infinite permutation groups arise in many parts of mathematics and continue to be a lively topic of research in their own right. The book begins with the basic ideas, standard constructions and important examples in the theory of permutation groups.It then develops the combinatorial and group theoretic structure of primitive groups leading to the proof of the pivotal O'Nan-Scott Theorem which links finite primitive groups with finite simple groups. Special topics covered include the Mathieu groups, multiply transitive groups, and recent work on the subgroups of the infinite symmetric groups. This text can serve as an introduction to permutation groups in a course at the graduate or advanced undergraduate level, or for self- study. It includes many exercises and detailed references to the current literature.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 364 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -The aim of this book is to discuss various aspects associated with disseminating personal or business data collected in censuses or surveys or copied from administrative sources. The problem is to present the data in such a form that they are useful for statistical research and to provide sufficient protection for the individuals or businesses to whom the data refer. The major part of this book is concerned with how to define the disclosure problem and how to deal with it in practical circumstances.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 172 pp. Englisch.

Buch. Condición: Neu. Neuware -The International Symposium on Biological Effects of Magnetic and Electrom- netic Fields was held from September 3-4, 1993 at Kyushu University in Fukuoka . Japan . Originally, it was only intended to be an informal gathering of many scientists who had accepted my invitation to visit Kyushu University after the XXIVth General Assembly of the International Union of Radio Science (URSI), held in Kyoto prior to our symposium . However, since so many distinguished scientists were able to come, it was decided that a more formal symposium would be possible . It was a very productive symposium and, as a result, many of the guests consented that it would be a good idea to gather all the information put forth at the meeting and have it published. In addition, although they were unfortunately unable to attend the symposium . many other distinguished scientists had also expressed their wish to contribute to this effort and, in so doing. help to increase understanding in this, as yet, relatively immature field of science . The question of both positive and negative effects of magnetic and electromagnetic fields on biological systems has become more and more important in our world today as they .Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 260 pp. Englisch.

Buch. Condición: Neu. Neuware -Over the years there has been a large increase in the functionality available on a single integrated circuit. This has been mainly achieved by a continuous drive towards smaller feature sizes, larger dies, and better packing efficiency. However, this greater functionality has also resulted in substantial increases in the capital investment needed to build fabrication facilities. Given such a high level of investment, it is critical for IC manufacturers to reduce manufacturing costs and get a better return on their investment. The most obvious method of reducing the manufacturing cost per die is to improve manufacturing yield.Modern VLSI research and engineering (which includes design manufacturing and testing) encompasses a very broad range of disciplines such as chemistry, physics, material science, circuit design, mathematics and computer science. Due to this diversity, the VLSI arena has become fractured into a number of separate sub-domains with little or no interaction between them. This is the case with the relationships between testing and manufacturing.From Contamination to Defects, Faults and Yield Loss: Simulation and Applications focuses on the core of the interface between manufacturing and testing, i.e., the contamination-defect-fault relationship. The understanding of this relationship can lead to better solutions of many manufacturing and testing problems.Failure mechanism models are developed and presented which can be used to accurately estimate probability of different failures for a given IC. This information is critical in solving key yield-related applications such as failure analysis, fault modeling and design manufacturing. 172 pp. Englisch.

Buch. Condición: Neu. Neuware -This book provides an introduction to the Monte Carlo method suitable for a one-or two-semester course for graduate and advanced undergraduate students in the mathematical and engineering sciences. It also can serve as a reference for the professional analyst. In the past, my inability to provide students with a single source book on this topic for class and for later professional reference had left me repeatedly frustrated, and eventually motivated me to write this book. In addition to focused accounts of major topics, the book has two unifying themes: One concerns the effective use of information and the other concerns error control and reduction. The book describes how to incorporate information about a problem into a sampling plan in a way that reduces the cost of estimating its solution to within a specified error bound. Although exploiting special structures to reduce cost long has been a hallmark of the Monte Carlo method, the propen sity of users of the method to discard useful information because it does not fit traditional textbook models repeatedly has impressed me. The present account aims at reducing the impediments to integrating this information. Errors, both statistical and computational, abound in every Monte Carlo sam pling experiment, and a considerable methodology exists for controlling them.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 728 pp. Englisch.

Buch. Condición: Neu. Neuware - THEBACKGROUND Why a book on Europe - Toward the Year 200l There are two principal reasons why a European should embark upon such a hazardous enterprise. First, when the Treaty on European Union (popularly known as the Maastricht Treaty, and, hereafter referred to as the Treaty in this introduction) was signed in February 1992, it was agreed that the heads of government of the EU Member States would assemble, in 1996, to examine its workings. This meeting will be known as the Intergovernmental Conference (IGC). Second, by the end of the century, it is certain that arrangements will have been made for the admission of some countries of Central and Eastern Europe into the European Union (EU). Consequently, even with or without the holding of the IGC, it will be urgently necessary to reform some of the Community's policies - notably the Common Agricultural Policy (CAP) and the structural poliCies which are linked, for example, 2 Europe - Toward 2001 with the Regional and Social Funds - before these countries become members. Failure to do this could result in bankruptcy for the EU. Of almost equal importance is the reform of the institutions and the actual workings of the Community. Already with 12 Member States, it was difficult enough to manage things on a daily basis. Now, as more countries join the Union, things could literally grind to a stop. Thus, changes in this area are indispensable.

Buch. Condición: Neu. Neuware -intense competition on banks and other financial institutions, as a period of oligopoly ends: more rather than less innovation is needed to help share undi versifiable risks, with more attention to correlations between different risks. Charles Goodhart of the London School of Economics (LSE), while ques tioning the idea that volatility has increased, concludes that structural changes have made regulation more problematic and calls for improved information availability on derivatives transactions. In a thirteen country case study of the bond market turbulence of 1994, Bo rio and McCauley of the BIS pin the primary causes of the market decline on the market's own dynamics rather than on variations in market participants' apprehensions about economic fundamentals. Colm Kearney of the Univer sity of Western Sydney, after a six country study of volatility in economic and financial variables, concludes that more international collaboration in man aging financial volatility (other than in foreign exchange markets) is needed in Europe. Finally, Stokman and Vlaar of the Dutch central bank investigate the empirical evidence for the interaction between volatility and international transactions in real and financial assets for the Netherlands, concluding that such influence depends on the chosen volatility measure. The authors sug gest that there are no strong arguments for international restrictions to reduce volatility. INSTITUTIONAL ISSUES AND PRACTICES The six papers in Part C focus on what market participants are doing to manage risk.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 390 pp. Englisch.

Buch. Condición: Neu. Neuware -It is critical for the food industry to maintain a current understanding of the factors affecting food choice, acceptance and consumption since these influence all aspects of its activities. This subject has matured in recent years and, for the first time, this book brings together a coherent body of knowledge which draws on the experiences in industrial and academic settings of an international team of authors. Written for food technologists and marketeers, the book is also an essential reference for all those concerned with the economic, social, and psychological aspects of the subject.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 412 pp. Englisch.

Buch. Condición: Neu. Neuware -Location, scheduling and design problems are assignment type problems with quadratic cost functions and occur in many contexts stretching from spatial economics via plant and office layout planning to VLSI design and similar prob lems in high-technology production settings. The presence of nonlinear inter action terms in the objective function makes these, otherwise simple, problems NP hard. In the first two chapters of this monograph we provide a survey of models of this type and give a common framework for them as Boolean quadratic problems with special ordered sets (BQPSs). Special ordered sets associated with these BQPSs are of equal cardinality and either are disjoint as in clique partitioning problems, graph partitioning problems, class-room scheduling problems, operations-scheduling problems, multi-processor assign ment problems and VLSI circuit layout design problems or have intersections with well defined joins as in asymmetric and symmetric Koopmans-Beckmann problems and quadratic assignment problems. Applications of these problems abound in diverse disciplines, such as anthropology, archeology, architecture, chemistry, computer science, economics, electronics, ergonomics, marketing, operations management, political science, statistical physics, zoology, etc. We then give a survey of the traditional solution approaches to BQPSs. It is an unfortunate fact that even after years of investigation into these problems, the state of algorithmic development is nowhere close to solving large-scale real life problems exactly. In the main part of this book we follow the polyhedral approach to combinatorial problem solving because of the dramatic algorith mic successes of researchers who have pursued this approach.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Buch. Condición: Neu. Neuware -Organic Inhibitors of Corrosion of Metals provides a detailed review of the various theories advanced to explain the mechanisms of organic inhibitors. Author Yu.I. Kuznetsov explores the role of potential and charge of the metal, the nature of the organic species used as the inhibitor, and the function of the solvent. The author draws connections between these key elements and the processes of passivation, pitting, synergism, and complex formation. This unique volume brings together the mechanistic and practical aspects of corrosion control by organic inhibitors.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 304 pp. Englisch.

Buch. Condición: Neu. Neuware -Batch manufactcring is a dominant manufacturing activity in the world, generating a great deal of industrial output. In the coming years, we are going to witness an era of mass customization of products. The major problems in batch manufacturing are a high level of product variety and small manufacturing lot sizes. The product variations present design engineers with the problem of designing many different parts. The decisions made in the design stage significantly affect manufacturing cost, quality and delivery lead times. The impacts of these product variations in manufacturing are high investment in equipment, high tooling costs, complex scheduling and loading, lengthy setup time and costs, excessive scrap and high quality control costs. However, to compete in a global market, it is essential to improve the productivity in small batch manufacturing industries. For this purpose, some innovative methods are needed to reduce product cost, lead time and enhance product quality to help increase market share and profitability. What is also needed is a higher level of integration of the design and manufacturing activities in a company. Group technology provides such a link between design and manufacturing. The adoption of group technology concepts, which allow for small batch production to gain economic advantages similar to mass production while retaining the flexibility of job shop methods, will help address some of the problems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 292 pp. Englisch.

Buch. Condición: Neu. Neuware -The notion of right-ordered groups is fundamental in theories of I-groups, ordered groups, torsion-free groups, and the theory of zero-divisors free rings, as well as in theoretical physics. Right-Ordered Groups is the first book to provide a systematic presentation of right-ordered group theory, describing all known and new results in the field. The volume addresses topics such as right-ordered groups and order permutation groups, the system of convex subgroups of a right-ordered group, and free products of right-ordered groups.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.

Buch. Condición: Neu. Neuware -HTML and the Art of Authoring For the World Wide Web is devoted to teaching the Web user how to generate good hypertext.`As a result of (this) rapid uncontrolled growth, the Web community may be facing a `hypertext crisis'. Thousands of hastily written or ill conceived documents may soon be presented to readers poorly formatted or unusable. .' (From the Preface.)`The clear and practical ways in which HTML and the Art of Authoring For the World Wide Web sets forth the principles of the Web, the operation of its servers and browsers, and its publishing concept is commendable. It will be an indispensable guide to the Web author as well as the sophisticated user.' (From the Foreword by Robert Cailliau.)`Despite its user friendliness, the Web has, by its own virtue, a default that makes it difficult for people to know where to begin: there is no starting point to the Web. Bebo White's HTML and the Art of Authoring For the World Wide Web will fill this gap immediately, as it provides a clear, introductory and sequential description of the fundamental concepts that lie underneath the Web. It describes HTML as an SGML application, explains the relationship between HTML and SGML, and gives a complete description of all the structure that HTML provides.' (From the Foreword by Eric van Herwijnen.)Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Buch. Condición: Neu. Neuware -Covering both theory and applications, this important work provides a comprehensive introduction to the modern theory of X-ray and electronic spectra of free atoms. Romas Karazija discusses methods of angular momenta, irreducible tensorial operators, and coefficients of fractional parentage and their use in determining cross sections and probabilities of elementary processes. In addition, Karazija addresses the structure of electronic shells with inner vacancies and many-body effects.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.

Buch. Condición: Neu. Neuware -Lifelong learning addresses situations in which a learner faces a series of different learning tasks providing the opportunity for synergy among them. Explanation-based neural network learning (EBNN) is a machine learning algorithm that transfers knowledge across multiple learning tasks. When faced with a new learning task, EBNN exploits domain knowledge accumulated in previous learning tasks to guide generalization in the new one. As a result, EBNN generalizes more accurately from less data than comparable methods. Explanation-Based Neural Network Learning: A Lifelong Learning Approach describes the basic EBNN paradigm and investigates it in the context of supervised learning, reinforcement learning, robotics, and chess.`The paradigm of lifelong learning - using earlier learned knowledge to improve subsequent learning - is a promising direction for a new generation of machine learning algorithms. Given the need for more accurate learning methods, it is difficult to imagine a future for machine learning that does not include this paradigm.'From the Foreword by Tom M. Mitchell.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 284 pp. Englisch.

Buch. Condición: Neu. Neuware -Biomechanics has a distinguished history extending at least to the 16th Century. However the later half oftbis century has seen an explosion ofthe field with it being viewed as affering exciting challenges for physical scientists and engineers interested in the life sciences, and wonderful opportunities for life scientists eager to collaborate with physical scientists and engineers and to render their scientific work more fundamental. That the field is now weil established and expanding is demonstrated by the formation of a World Committee for Biomechanics and the success and large participation in the 1st and 2nd World Congresses of Biomechanics, held respectively in San Diego in 1990 and in Amsterdam in 1994. With more than 1350 scientific papers delivered at the 2nd World Congress, either within symposia or oral or poster sessions, it would have been out of the question to try to produce comprehensive edited proceedings. Moreover, we are confident that most of the papers have been or will be published in one ofthe excellentjoumals covering the field. But of effort contributed by the plenary lecturers and the tutorial we thought that the large amount and keynote speakers of various symposia deserved tobe recognised in the form of a specific publication, thus also allowing those unable to attend the presentatiops . . tC sh r~ in the findings. Furthermore, we feel that there is now a need to review aspects 'oftlie freld.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 380 pp. Englisch.

Buch. Condición: Neu. Neuware -Food processing is now the biggest industry in the UK and in many other countries. It is also rapidly changing from what was essentially a craft industry, batch processing relatively small amounts of product, to a very highly automated one with continuously operating high speed production lines. In addition, consumers have developed a greater expectation for consistently high standard products and coupled this with demands for such things as a more natural flavour, lower fat etc. The need for an increased knowledge of the scientific principles behind food processing has never been greater. Within the industry itself, increased automation, company diversification and amalgamations etc. have meant that those working in it have often to change their field of operation. Whereas twenty years ago, someone starting work in one branch of the food industry could expect, if he or she so desired, to work there all their working lives, this is now seldom the case. This means that a basic knowledge of the principles behind food processing is necessary both for the student at university or college, and for those already in the industry. It is hoped, therefore, that this book will appeal to both, and prove to be a useful reference over a wide range of food processing. 488 pp. Englisch.

Buch. Condición: Neu. Neuware -The 7th International Symposium on Platinum and other metal coordination compounds in Cancer Chemotherapy, ISPCC '95, organized by the European Cancer Centre, was held in Amsterdam, the Netherlands, March 1-4, 1995. As with previous ISPCC meetings, the goal of ISPCC '95 was to bring together c1inicians, clinical investigators, scientists, and laboratory workers from many disciplines to promote further collaboration and cooperation in the development of new platinum and other metal coordination compounds as weil as in new ways to use 'c1assical' drugs as cisplatin and carboplatin in the treatment of cancer. Important aspects addressed by experts in the field inc1uded the synthesis and activity of new platinum compounds, the biochemistry and molecular pharrnacology as weil as the c1inical pharrnacology of this c1ass of antineoplastic agents, an overview of current c1inical studies, one special minisymposium on the mechanisms of cell kill of platinum, and one on resistance against platinum compounds. Finally, the current status of development of nonplatinum metal complexes was discussed. This volume contains the contributions of the various speakers at ISPCC '95 and provides an up-to-date and comprehensive overview of this important c1ass of anticancer agents, ranging from synthesis and molecular pharrnacology on one hand to c1inical pharrnacology and cIinical investigations on the other hand. The Organizing Corrunittee and Editors wish to express their gratitude to the contributors to this volume, to the various organizations and pharrnaceutical companies for their generous sponsoring of ISPCC '95, and to the Plenum Publishing Company for their help in producing this volume.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 372 pp. Englisch.

Buch. Condición: Neu. Neuware -As indicated in the Foreword to this series on Advances in Pulsed Power Technologies, the pioneering roots of modern pulsed power as related by J.C. 'Charlie' Martin and his co-workers of the Atomic Weapons Research Establishment, Aldermaston, Reading UK is an important if not essential record of the experiential history of the major developer of pulsed power advances during the post-World War II period. It finds great utility as an instructive accounting of the trials, tribulations and, finally, an almost chronological walk through their thoughts as they diligently and happily travel the yellow brick road to success. It is recounted in the inimitable style of 'Charlie' Martin as only he can relate, with some insightful perspectives by Mike Good man, a constant companion, and collaborator who shares his unique view of 'Charlie' and the Aldermaston Group. This collection of selected articles is unique, for in large part, the documentation of their struggle and final triumph have not been formerly published in any archival manner. One reason, we suspect, was the defense-related application and significance of their work, compounded by the constant need for progress which did not allow for the time consuming preparation of formal submission to the literature. This also explains the 'urgent' and sometimes terse manner of their writings. Yet the material remains remarkably current because we are dealing, in large measure, with pulsed systems less sensitive to those factors involved in slower pulsed scenarios.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 572 pp. Englisch.

Buch. Condición: Neu. Neuware - Multimedia computing has emerged in the last few years as a major area of research. Multimedia computer systems have opened a wide range of applications by combining a variety of information sources, such as voice, graphics, animation, images, audio, and full-motion video. Looking at the big picture, multimedia can be viewed as the merging of three industries: the computer, communications, and broadcasting industries. Research and development efforts in multimedia computing can be divided into two areas. As the first area of research, much effort has been centered on the stand-alone multimedia workstation and associated software systems and tools, such as music composition, computer-aided education and training, and interactive video. However, the combination of multimedia computing with distributed systems offers even greater potential. New applications based on distributed multimedia systems include multimedia information systems, collaborative and videoconferencing systems, on-demand multimedia services, and distance learning. Multimedia Tools and Applications is one of two volumes published by Kluwer, both of which provide a broad introduction to this fast moving area. This book covers selected tools applied in multimedia systems and key multimedia applications. Topics presented include multimedia application development techniques, techniques for content-based manipulation of image databases, techniques for selection and dissemination of digital video, and tools for digital video segmentation. Selected key applications described in the book include multimedia news services, multimedia courseware and training, interactive television systems, digital video libraries, multimedia messaging systems, and interactive multimedia publishing systems. The second book, Multimedia Systems and Techniques, covers fundamental concepts and techniques used in multimedia systems. The topics include multimedia objects and related models, multimedia compression techniques and standards, multimedia interfaces, multimedia storage techniques, multimedia communication and networking, multimedia synchronization techniques, multimedia information systems, scheduling in multimedia systems, and video indexing and retrieval techniques. Multimedia Tools and Applications, along with its companion volume, is intended for anyone involved in multimedia system design and applications and can be used as a textbook for advanced courses on multimedia.

Buch. Condición: Neu. Neuware - Multithreaded Processor Design takes the unique approach of designing a multithreaded processor from the ground up. Every aspect is carefully considered to form a balanced design rather than making incremental changes to an existing design and then ignoring problem areas. The general purpose parallel computer is an elusive goal. Multithreaded processors have emerged as a promising solution to this conundrum by forming some amalgam of the commonplace control-flow (von Neumann) processor model with the more exotic data-flow approach. This new processor model offers many exciting possibilities and there is much research to be performed to make this technology widespread. Multithreaded processors utilize the simple and efficient sequential execution technique of control-flow, and also data-flow like concurrency primitives. This supports the conceptually simple but powerful idea of rescheduling rather than blocking when waiting for data, e.g. from large and distributed memories, thereby tolerating long data transmission latencies. This makes multiprocessing far more efficient because the cost of moving data between distributed memories and processors can be hidden by other activity. The same hardware mechanisms may also be used to synchronize interprocess communications to awaiting threads, thereby alleviating operating system overheads. Supporting synchronization and scheduling mechanisms in hardware naturally adds complexity. Consequently, existing multithreaded processor designs have tended to make incremental changes to existing control-flow processor designs to resolve some problems but not others. Multithreaded Processor Design serves as an excellent reference source and is suitable as a text for advanced courses in computer architecture dealing with the subject.

Buch. Condición: Neu. Neuware - Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life. In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.

Buch. Condición: Neu. Neuware - Broadband communications is widely recognized as one of the most revolutionary emerging technologies of the last decade of the 20th century. This book provides a comprehensive snapshot of leading-edge research across a structured set of topics vital to broadband communications infrastructure for the information age.

Buch. Condición: Neu. Neuware -''Excellent and very timely.It will undoubtedly become a standard reference for the application of circular dichroism (CD) to biomolecules.'' --- Quarterly Review of Biology, March 1997 ''[T]estament to the book's utility is the fact that during the course of my review I had to 'rescue' it from the desks of graduate students on an almost daily basis. In summary, this is a great book.'' --- American Scientist ''Well documented chapters provide a very good insight into the problems surrounding the conformation of biomacromolecules.An indispensible source of information.'' --- Nahrung, 42(2), 1998 Renowned experts present the first state-of-the-art description of circular dichroism spectroscopy (CD). Chapters present in-depth discussions of the history of the field, the theory of CD for application to globular proteins, membrane proteins, peptides, nucleic acids and their interactions, carbohydrates, and instrumentation. Discussions also feature new techniques using synchrotron radiation, vibrational Raman optical activity, and vibrational CD. More than 250 illustrations supplement the text.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 756 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In vitro and animal studies show that vanadate and other Because most cellular components contain hydroxyl and/or vanadium compounds increase glucose transport activity and phosphate groups, vanadate reacts as shown in eq. 1, and 2 normalize glucose metabolism [1-5]. Furthermore, these with a variety of metabolites. For example, the reaction of insulin-mimetic compounds can be administered orally. Vana vanadate with the 2'-hydroxyl group of the cofactor NAD date enhances the phosphoprotein formation which is attrib generates an NADP analog, NADV (path b) [22]. NADV is uted to either the activation of protein kinases or inhibition an excellent cofactor for enzymes such as glucose-6-phos of protein phosphatases. Despite the interest in document phate dehydrogenase, 6-phosphogluconate dehydrogenase, ing the effects of vanadate on protein kinases, most reports and alcohol dehydrogenase [22]. The presence ofNADV have used indirect methods and studies with purified kinases could affect the levels of reducing equivalents in the cell, im show weak, if any, interaction of vanadate with kinases as portant in maintaining a normal glucose metabolism. This a group of enzymes (reviewed in Refs. [6-8]). Vanadate type of mechanism is distinct from the vanadate-induced interacts potently with phosphatases and the inhibition is NADH oxidation by plasma membranes [23]. Organic attributed to a five-coordinate vanadate complex which vanadates have been shown to substitute for organic phos mimics the transition state of the phosphate ester hydroly phates in many of the enzymes related to glucose metabolism sis reaction (reviewed in Refs. [7,9]).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Representations of Discrete Functions is an edited volume containing 13 chapter contributions from leading researchers with a focus on the latest research results. The first three chapters are introductions and contain many illustrations to clarify concepts presented in the text. It is recommended that these chapters are read first. The book then deals with the following topics: binary decision diagrams (BDDs), multi-terminal binary decision diagrams (MTBDDs), edge-valued binary decision diagrams (EVBDDs), functional decision diagrams (FDDs), Kronecker decision diagrams (KDDs), binary moment diagrams (BMDs), spectral transform decision diagrams (STDDs), ternary decision diagrams (TDDs), spectral transformation of logic functions, other transformations oflogic functions, EXOR-based two-level expressions, FPRM minimization with TDDs and MTBDDs, complexity theories on FDDs, multi-level logic synthesis, and complexity of three-level logic networks. Representations of Discrete Functions is designed for CAD researchers and engineers and will also be of interest to computer scientists who are interested in combinatorial problems. Exercises prepared by the editors help make this book useful as a graduate level textbook. 356 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -High Performance Computational Methods for Biological Sequence Analysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field. This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes. High Performance Computational Methods for Biological Sequence Analysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses. 236 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It. is well known that t.he introduction of a new technology in one organization not always produces the intended benefits (Levine, 1994). In many cases, either the receivers do not reach the intended level of use or simply the technology is rejected because it does not match with the expectations (true or false) and the accepted psychological effort to use it. The case of formal methods is a paradigmatic example of continual failures. The published cases with problems or failures only constitute the visible part of a large iceberg of adoption cases. It. is difficult to get companies to openly express the problems they had; however, from the experience of the author, failure cases are very common and they include any type of company. Many reasons to explain the failures (and in some cases the successes) could be postulated; however, the experiences are not structured enough and it is difficult to extract from them useful guidelines for avoiding future problems. Generally speaking, there is a trend to find the root of the problems in the technol ogy itself and in its adequacy with the preexistent technological context. Technocratic technology transfer models describe the problems in terms of these aspects. Although it is true that those factors limit the probability of success, there is another source of explanations linked to the individuals and working teams and how they perceive the technology. 232 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This major reference work represents the first attempt to confront, on a world-wide basis, the way computer associations face up to their own responsibilities in an age increasingly dominated by information and communication technology. The book deals with the codes of ethics and conduct, and related issues. It is the first book to deal with homogenous codes namely codes of national computer societies. Some thirty codes are compared and analysed in depth. To put these into perspective, there are discussion papers covering the methodological, philosophical and organisational issues.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.