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Transporters in Drug Discovery and Development

LAI, YURONG

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ISBN 10: 1907568212 / ISBN 13: 9781907568213
Editorial: Woodhead Publishing, 2013
Nuevos Condición: NEW Encuadernación de tapa dura
Librería: Herb Tandree Philosophy Books (Stroud, GLOS, Reino Unido)

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9781907568213 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. N° de ref. de la librería HTANDREE0902078

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Título: Transporters in Drug Discovery and ...

Editorial: Woodhead Publishing

Año de publicación: 2013

Encuadernación: Hardback

Condición del libro:NEW

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Sinopsis:

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.

  • A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development
  • Balanced coverage of molecular biology aspects and functional outcomes
  • State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity

About the Author:

Yurong Lai is a senior principal scientist at a US-based pharmaceutical company. He received his M.D. from Fujian Medical University in China and a Ph.D. (Toxicology) from Sapporo Medical University in Japan. From 1998 to 2001, he was a research fellow of Japanese Society for Promotion (JSPS) in Department of Physiopathology, Graduate School of Medicine of Hokkaido University, followed by a position as Research Associate in Department of Pharmaceutics, University of Washington

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