Transcription Factors: Normal and Malignant Development of Blood Cells (Hardcover)

Jacob Licht

ISBN 10: 0471350540 / ISBN 13: 9780471350545
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Hardcover. The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearr.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 640 pages. 1.324. N° de ref. de la librería

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Sinopsis: The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies).

Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.

This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:

  • Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
  • Leukemias due to chromosomal translocations involving gene encoding transcription factors
  • Oncogenesis and hematopoiesis
  • In vivo studies of transcription factors implicated in hematopoiesis
  • And much more

Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.

From the Back Cover: Transcription Factors

Normal and Malignant Development of Blood Cells

Katya Ravid and Jonathan Licht

The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.

This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
* Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
* Leukemias due to chromosomal translocations involving gene encoding transcription factors
* Oncogenesis and hematopoiesis
* In vivo studies of transcription factors implicated in hematopoiesis
* And much more

Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.

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Detalles bibliográficos

Título: Transcription Factors: Normal and Malignant ...
Año de publicación: 2000
Encuadernación: Hardcover
Condición del libro: New
Edición: 1st.

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Ravid, Katya, Licht, Jonathan D., eds.
Editorial: Wiley-Liss (2000)
ISBN 10: 0471350540 ISBN 13: 9780471350545
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Descripción Wiley-Liss, 2000. Estado de conservación: Good. *Price HAS BEEN reduced by 10% until Monday, Sept. 25. Order now for BEST SAVINGS!* 640 pp., Hardcover, ex library, else text clean and binding tight. Nº de ref. de la librería ZB904821

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Descripción Wiley-Blackwell, 2001. Hardcover. Estado de conservación: Good. Sent within 24 hours. Expedited UK delivery available. No Dustjacket. Nº de ref. de la librería BBI2485653

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Descripción New York : Wiley, 2001. Hardcover. xv, 622 p. Good. Ex-library with usual library markings. Guter Zustand. Bibliotheks-Exemplar mit Stempel und Signaturaufkleber. Sprache: Englisch Gewicht in Gramm: 1400. Nº de ref. de la librería 73983

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Descripción Wiley-Liss, 2000. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería M0471350540

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Descripción Estado de conservación: Good. Transcription Factors: Normal and Malignant Development of Blood Cells (Wiley-Liss Publication). Nº de ref. de la librería Grb0903491

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Editor-Katya Ravid; Editor-Jonathan D. Licht
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Descripción Wiley-Liss, 2000. Hardcover. Estado de conservación: Used: Good. Nº de ref. de la librería SONG0471350540

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Descripción Wileyand#8211;Blackwell, 2001. HRD. Estado de conservación: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Nº de ref. de la librería FW-9780471350545

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Descripción John Wiley and Sons Ltd, United States, 2001. Hardback. Estado de conservación: New. New.. Language: English . Brand New Book. Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias. This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as: Transcription factors and the megakaryocytic, myeloid, and erythroid lineages Leukemias due to chromosomal translocations involving gene encoding transcription factors Oncogenesis and hematopoiesis In vivo studies of transcription factors implicated in hematopoiesis And much more Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation. Nº de ref. de la librería AAH9780471350545

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Editorial: John Wiley and Sons Ltd, United States (2001)
ISBN 10: 0471350540 ISBN 13: 9780471350545
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Descripción John Wiley and Sons Ltd, United States, 2001. Hardback. Estado de conservación: New. New.. Language: English . Brand New Book. Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias. This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as: Transcription factors and the megakaryocytic, myeloid, and erythroid lineages Leukemias due to chromosomal translocations involving gene encoding transcription factors Oncogenesis and hematopoiesis In vivo studies of transcription factors implicated in hematopoiesis And much more Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation. Nº de ref. de la librería AAH9780471350545

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