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Neural Transplantation in Cerebellar Ataxia

LAZAROS TRIARHOU

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ISBN 10: 3662222159 / ISBN 13: 9783662222157
Editorial: Springer, 2013
Nuevos Condición: NEW Encuadernación de tapa blanda
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Herb Tandree Philosophy Books
Stroud, GLOS, Reino Unido

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9783662222157 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. N° de ref. de la librería HTANDREE0409854

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Título: Neural Transplantation in Cerebellar Ataxia

Editorial: Springer

Año de publicación: 2013

Encuadernación: Paperback

Condición del libro: NEW

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Sinopsis:

erebellar ataxia is a failure in muscular coordination that re­ C sults from a slow, progressive deterioration of neurons in the cerebellum. An estimated 150,000 people are affected by the he­ reditary ataxias and related disorders in the United States. At present, there is no known cure. In an experimental treatment aimed at reconstructing the damaged pathway through exog­ enous neuronal supplementation, genetically ataxic mice have been used for intracerebral grafting of genetically healthy cerebellar neuroblasts, and evidence has been obtained for graft-induced en­ hancement of behavioral responses after bilateral cerebellar grafts. Such results are encouraging and underscore the potential of the neural grafting technique in restoring cerebellar function. How­ ever, many of the pathological and biochemical mechanisms in the interaction between grafted tissue and the host brain need to be further elucidated in extensive experimental studies, and great cau­ tion must be used in contemplating the theoretical feasibility of a possible application in humans.

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Fromehall Mill, Blk 2, Rm 9 - Lodgemore Lane - Stroud, Glos. GL5 3EH, U.K.
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