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Nanosuspension Formulation for the Management of Hypertension (Paperback)

Pandya Vikram M, Bharadia Praful, Thakkar Divyesh

ISBN 10: 365933829X / ISBN 13: 9783659338298
Editorial: LAP Lambert Academic Publishing, United States, 2013
Nuevos Condición: New Encuadernación de tapa blanda
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Language: English . Brand New Book. Hypertension is one of the primary risk factors for heart disease and stroke, the leading causes of death worldwide. Telmisartan is BCS class II, anti-hypertensive drug.The aim of present work was to develop a Telmisartan nanosuspension for faster onset of action which is essential in hypertension condition. In the present work nanosuspension is prepared by media milling method. Zirconium oxide beads are used as milling media. The optimization was done using 3level3 factor full factorial design.The optimized batch shown particle size is 356 nm, Zeta potential -8.3 and drug release after 10 min is 64.20 . N° de ref. de la librería KNV9783659338298

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Título: Nanosuspension Formulation for the ...

Editorial: LAP Lambert Academic Publishing, United States

Año de publicación: 2013

Encuadernación: Paperback

Condición del libro:New

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Hypertension is one of the primary risk factors for heart disease and stroke, the leading causes of death worldwide. Telmisartan is BCS class II, anti-hypertensive drug.The aim of present work was to develop a Telmisartan nanosuspension for faster onset of action which is essential in hypertension condition. In the present work nanosuspension is prepared by media milling method. Zirconium oxide beads are used as milling media. The optimization was done using 3level3 factor full factorial design.The optimized batch shown particle size is 356 nm,Zeta potential -8.3 and % drug release after 10 min is 64.20%.

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