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Mucoadhesive Bilayer Lidocaine Buccal Tablet to Treat Gum Diseases

Nahid Sharmin

ISBN 10: 3846553972 / ISBN 13: 9783846553978
Editorial: LAP LAMBERT Academic Publishing
Nuevos Condición: New Encuadernación de tapa blanda
Librería: BuySomeBooks (Las Vegas, NV, Estados Unidos de America)

Librería en AbeBooks desde: 21 de mayo de 2012

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Descripción

Paperback. 164 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.The focus of the pharmaceutical research is being steadily shifted from the development of new chemical entities to novel drug delivery systems of existing drug molecules to maximize their effectiveness in terms of therapeutic action and patent protection. This is made possible by the discovery of various compatible polymers (e. g. Carbopol polymers). Local delivery of the anesthetic agent(e. g. Lidocaine)leads to higher concentration of the drug at the intended site of action using a lower dose with an associated reduction in side effects relative to systemic administration. One of the most critical factors in enhancing the efficacy of a topical anesthetic is maintaining prolonged intraoral mucosal contact. Most topical agents come in gel form, which is difficult to localize to a particular site and easily diluted by saliva. To overcome these problems, bilayer buccal tablets were prepared with carbopol polymer. They seem to solve all these problems associated with the treatment of gingivitis and other periodontal diseases and adhere well to the gum and control the release of the drug for an extended period of time. Besides this, characteristics of carbopol polymers were also evaluated. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. N° de ref. de la librería 9783846553978

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Detalles bibliográficos

Título: Mucoadhesive Bilayer Lidocaine Buccal Tablet...

Editorial: LAP LAMBERT Academic Publishing

Encuadernación: Paperback

Condición del libro:New

Tipo de libro: Paperback

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Sinopsis:

The focus of the pharmaceutical research is being steadily shifted from the development of new chemical entities to novel drug delivery systems of existing drug molecules to maximize their effectiveness in terms of therapeutic action and patent protection. This is made possible by the discovery of various compatible polymers (e.g. Carbopol polymers). Local delivery of the anesthetic agent(e.g.Lidocaine)leads to higher concentration of the drug at the intended site of action using a lower dose with an associated reduction in side effects relative to systemic administration.One of the most critical factors in enhancing the efficacy of a topical anesthetic is maintaining prolonged intraoral mucosal contact. Most topical agents come in gel form, which is difficult to localize to a particular site and easily diluted by saliva.To overcome these problems, bilayer buccal tablets were prepared with carbopol polymer.They seem to solve all these problems associated with the treatment of gingivitis and other periodontal diseases and adhere well to the gum and control the release of the drug for an extended period of time. Besides this,characteristics of carbopol polymers were also evaluated.

About the Author:

Nahid Sharmin has completed B.Pharm and M.Pharm (Department of Pharmaceutical Technology) from the University of Dhaka of Bangladesh.She worked in various fields of novel drug delivery technology.Her thesis topic was mucoadhesive drug delivery system and since then she has been working on this. She has several publications in reputed journals.

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