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Modernising the Monograph for Cetomacrogol Cream BP 1980, Formulation a

Ameya Pachhade

ISBN 10: 3659398152 / ISBN 13: 9783659398155
Editorial: LAP Lambert Academic Publishing
Nuevos Condición: New Encuadernación de tapa blanda
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Paperback. 56 pages. Dimensions: 8.7in. x 5.9in. x 0.1in.A monograph for cetomacrogol cream has been omitted from the British Pharmacopoeia (BP) since 1980. Products containing this cream as a base are still available on the market, for example Bactroban cream. Hence, there is a need to update monograph for cetomacrogol cream. For this purpose Cetomacrogol Cream BP, formula A was analysed with different test methods. The BP formula B was not available commercially for comparison. This cream was tested for various parameters: appearance, texture, pH value, melting and freezing points, sulphated ash value, and viscosity. It has been found that these tests show useful results and should be included in a new monograph. Results obtained show relevance to use in determining storage conditions, which can be incorporated on the label of this product. Attempts to determine quantitative analysis using HPLC-UV, HPLC-MS and UV- spectroscopy showed no useful results. The reasons behind this can be absence of aromatic group in cream detectable by UV and the presence of many different chain lengths of cetomacrogol makes MS spectrum meaningless. The study demonstrates parameters and ways by which monograph for cetomacrogol cream can be updated. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. N° de ref. de la librería 9783659398155

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Detalles bibliográficos

Título: Modernising the Monograph for Cetomacrogol ...

Editorial: LAP Lambert Academic Publishing

Encuadernación: Paperback

Condición del libro: New

Tipo de libro: Paperback

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Sinopsis:

A monograph for cetomacrogol cream has been omitted from the British Pharmacopoeia (BP) since 1980. Products containing this cream as a base are still available on the market, for example Bactroban cream®. Hence, there is a need to update monograph for cetomacrogol cream. For this purpose Cetomacrogol Cream BP, formula A was analysed with different test methods. The BP formula B was not available commercially for comparison. This cream was tested for various parameters: appearance, texture, pH value, melting and freezing points, sulphated ash value, and viscosity. It has been found that these tests show useful results and should be included in a new monograph. Results obtained show relevance to use in determining storage conditions, which can be incorporated on the label of this product. Attempts to determine quantitative analysis using HPLC-UV, HPLC-MS and UV- spectroscopy showed no useful results. The reasons behind this can be absence of aromatic group in cream detectable by UV and the presence of many different chain lengths of cetomacrogol makes MS spectrum meaningless. The study demonstrates parameters and ways by which monograph for cetomacrogol cream can be updated.

About the Author:

-Age 25.-B.Pharmacy and MSc Pharmaceutical Science, with Commendation, from London, UK. -At the age of 23, DIRECTOR at VEEMAL ENTERPRISES, health care device manufacturing company in India. -Holds a PATENT application. -Developed 4 devices by own. -Willing to develop career internationally in the field of Clinical Research.

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