Metabolism in Cancer (Hardback)

Editorial: Springer International Publishing AG, 2016
ISBN 10: 3319421166 / ISBN 13: 9783319421162
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Descripción:

Language: English. Brand new Book. This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy. N° de ref. de la librería LIB9783319421162

Sobre este título:

Sinopsis: THIS TEXTBOOK PRESENTS CONCISE CHAPTERS WRITTEN BY INTERNATIONALLY RESPECTED EXPERTS ON VARIOUS IMPORTANT ASPECTS OF CANCER-ASSOCIATED METABOLISM, OFFERING A COMPREHENSIVE OVERVIEW OF THE CENTRAL FEATURES OF THIS EXCITING RESEARCH FIELD. THE DISCOVERY THAT TUMOR CELLS DISPLAY CHARACTERISTIC ALTERATIONS OF METABOLIC PATHWAYS HAS SIGNIFICANTLY CHANGED OUR UNDERSTANDING OF CANCER: WHILE THE FIRST DESCRIPTION OF TUMOR-SPECIFIC CHANGES IN CELLULAR ENERGETICS WAS PUBLISHED MORE THAN 90 YEARS AGO, THE CAUSAL SIGNIFICANCE OF THIS OBSERVATION FOR THE PATHOGENESIS OF CANCER WAS ONLY DISCOVERED IN THE POST-GENOME ERA. THE FIRST 10 YEARS OF THE TWENTY-FIRST CENTURY WERE CHARACTERIZED BY RAPID ADVANCES IN OUR GRASP OF THE FUNCTIONAL ROLE OF CANCER-SPECIFIC METABOLISM AS WELL AS THE UNDERLYING MOLECULAR PATHWAYS. VARIOUS UNANTICIPATED INTERRELATIONS BETWEEN METABOLIC ALTERATIONS AND CANCER-DRIVING PATHWAYS WERE IDENTIFIED AND CURRENTLY AWAIT TRANSLATION INTO DIAGNOSTIC AND THERAPEUTIC APPLICATIONS. YET THE SPEED, QUANTITY, AND COMPLEXITY OF THESE NEW DISCOVERIES MAKE IT DIFFICULT FOR RESEARCHERS TO KEEP UP TO DATE WITH THE LATEST DEVELOPMENTS, AN ISSUE THIS BOOK HELPS TO REMEDY.

Reseña del editor: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

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Detalles bibliográficos

Título: Metabolism in Cancer (Hardback)
Editorial: Springer International Publishing AG
Año de publicación: 2016
Encuadernación: Hardback
Condición del libro: New
Edición: 1st ed. 2016.

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