Gastroretentive Dosage Forms: Floating Tablets

ISBN 10: 3659120383 / ISBN 13: 9783659120381
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Sinopsis: Historically, oral drug administration has been the predominant route for drug delivery. Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, for example treatment of peptic ulcer disease. Furthermore, improved bioavailability is expected for drugs that are absorbed readily upon release in the GI tract. These drugs can be delivered ideally by slow release from the stomach. Many drugs categorised as once-a-day delivery have been demonstrated to have suboptimal absorption due to dependence on the transit time of the dosage form, These drugs can be delivered ideally by slow release from the stomach.

Biografía del autor: He is currently a PhD scholar (Pharmaceutics) and doing research work in Department of Pharmacy in Vikarm University, Ujjain (India) and taught Pharmaceutics, Pharma-tech, Bio-pharmaceutics. Previously, he has worked in pharmaceutical industry in production department. He has published several research & review articles in various renowned journals

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Título: Gastroretentive Dosage Forms: Floating ...
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Descripción LAP Lambert Academic Publishing, Germany, 2012. Paperback. Estado de conservación: New. Aufl.. 220 x 150 mm. Language: English . Brand New Book ***** Print on Demand *****.Historically, oral drug administration has been the predominant route for drug delivery. Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, for example treatment of peptic ulcer disease. Furthermore, improved bioavailability is expected for drugs that are absorbed readily upon release in the GI tract. These drugs can be delivered ideally by slow release from the stomach. Many drugs categorised as once-a-day delivery have been demonstrated to have suboptimal absorption due to dependence on the transit time of the dosage form, These drugs can be delivered ideally by slow release from the stomach. Nº de ref. de la librería AAV9783659120381

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Descripción LAP LAMBERT Academic Publishing. Paperback. Estado de conservación: New. Paperback. 68 pages. Dimensions: 8.7in. x 5.9in. x 0.2in.Historically, oral drug administration has been the predominant route for drug delivery. Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, for example treatment of peptic ulcer disease. Furthermore, improved bioavailability is expected for drugs that are absorbed readily upon release in the GI tract. These drugs can be delivered ideally by slow release from the stomach. Many drugs categorised as once-a-day delivery have been demonstrated to have suboptimal absorption due to dependence on the transit time of the dosage form, These drugs can be delivered ideally by slow release from the stomach. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Nº de ref. de la librería 9783659120381

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Descripción Estado de conservación: Good. Gastroretentive Dosage Forms: Floating Tablets. Nº de ref. de la librería Grb3794892

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Descripción LAP LAMBERT Academic Publishing, 2012. Paperback. Estado de conservación: Used: Good. This item is printed on demand. Nº de ref. de la librería SONG3659120383

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