Imagen del editor

Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery (Hardback)

Ewelina Guca

0 valoraciones por Goodreads
ISBN 10: 3527339043 / ISBN 13: 9783527339044
Editorial: John Wiley and Sons Ltd, United Kingdom, 2016
Nuevos Condición: New Encuadernación de tapa dura
Librería: The Book Depository EURO (London, Reino Unido)

Librería en AbeBooks desde: 29 de abril de 2014

Cantidad disponible: 1

Comprar nuevo
Precio: EUR 240,61 Convertir moneda
Gastos de envío: EUR 3,40 De Reino Unido a Estados Unidos de America Destinos, gastos y plazos de envío
Añadir al carrito

Descripción

Language: English . Brand New Book. Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art omics technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented. N° de ref. de la librería AAS9783527339044

Hacer una pregunta a la librería

Detalles bibliográficos

Título: Comprehensive Analysis of Parasite Biology: ...

Editorial: John Wiley and Sons Ltd, United Kingdom

Año de publicación: 2016

Encuadernación: Hardback

Condición del libro:New

Edición: 1. Auflage.

Acerca de

Sinopsis:

WRITTEN AND EDITED BY EXPERTS IN THE FIELD, THIS BOOK BRINGS TOGETHER THE CURRENT STATE OF THE ART IN PHENOTYPIC AND RATIONAL, TARGET–BASED APPROACHES TO DRUG DISCOVERY AGAINST PATHOGENIC PROTOZOA. THE CHAPTERS FOCUS PARTICULARLY ON VIRTUAL COMPOUNDS AND HIGH THROUGHPUT SCREENING, NATURAL PRODUCTS, COMPUTER–ASSISTED DRUG DESIGN, STRUCTURE–BASED DRUG DESIGN, MECHANISM OF ACTION IDENTIFICATION, AND PATHWAY MODELLING. FURTHERMORE, STATE–OF THE ART "OMICS" TECHNOLOGIES ARE DESCRIBED AND CURRENTLY STUDIED ENZYMATIC DRUG TARGETS ARE DISCUSSED. MATHEMATICAL, SYSTEMS BIOLOGY–BASED APPROACHES ARE INTRODUCED AS NEW METHODOLOGIES FOR DISSECTING COMPLEX ASPECTS OF PATHOGEN SURVIVAL MECHANISMS AND FOR TARGET IDENTIFICATION. IN ADDITION, RECENTLY DEVELOPED ANTI–PARASITIC AGENTS TARGETING PARTICULAR PATHWAYS, WHICH SERVE AS LEAD COMPOUNDS FOR FURTHER DRUG DEVELOPMENT, ARE PRESENTED.

Críticas:

"In summary, this book illustrates why it is extremely beneficial to 1) precisely understand the biology of a host-parasite unit and 2) combine a set of powerful alternative approaches for drug development as well as target identification and validation. In his foreword, Graham Coombs recommends that more experienced scientists should be encouraging those in the early stages of their career to remember appropriate past work, read books and not to forget the basic biology when applying novel approaches. I fully agree. Read this book" Prof. Dr. Marcel Deponte, Technische Universit-t Kaiserslautern, ChemMedchem, Sept 2017

"Sobre este título" puede pertenecer a otra edición de este libro.

Descripción de la librería

The Book Depository - bookdepository.com - is the UK's largest dedicated online bookseller offering the largest range of titles in the world, available for dispatch within 48 hours. Founded in 2004 to make 'All Books To All' we focus on selling 'less of more' rather than 'more of less', differentiating ourself from other retailers who increasingly focus on bestsellers. All books available to All Currently, The Book Depository is able to ship over 4 million unique titles, within 48 hours, from our fulfillment centre in Gloucester, United Kingdom. This figure is increasing everyday. Apart from publishers, distributors and wholesalers, we even list and supply books from other retailers!

Ver la página web de la librería

Condiciones de venta:

All books are shipped in New condition promptly, we are
happy to accept returns up to 30 days from purchase. Orders
usually ship within 1-2 business days. Domestic Shipments
are sent by Royal Mail, and International by Priority
Airmail. We are happy to accept returns up to 30 days from
purchase.

¿ Name of business : The Book Depository Ltd
¿ Form of legal entity : A Limited Company
¿ Business address: The Book Depository, Thames Central, Hatfield Road,
Slough, Berkshire, SL1 1QE
¿ Email address:...

Más información
Condiciones de envío:

Orders usually ship within 1-2 business days. Domestic Shipments are sent by Royal
Mail, and International by Priority Airmail. Orders usually ship within 1-2
business days. Domestic Shipments are sent by Royal Mail, and International by
Priority Airmail. We are happy to accept returns up to 30 days from purchase.
Please contact the seller directly if you wish to return an order.

Todos los libros de esta librería

Métodos de pago
aceptados por la librería

Visa Mastercard American Express Carte Bleue