Ambroxol HCl SR Tablet - Tapa blanda

Akhter, Dewan Taslima; Huda, Naz Hasan; Ahmed, Tajnin

 
9783847346067: Ambroxol HCl SR Tablet
Tapa blanda
ISBN 10: 3847346067 ISBN 13: 9783847346067
Editorial: LAP Lambert Academic Publishing, 2012

Sinopsis

The purpose of the present investigation was to design and evaluate sustained release tablets of a sparingly water soluble drug Ambroxol Hydrochloride, two hydrophilic polymers METHOCEL K15MCR and METHOCEL K100MCR and hydrophobic Eudragit RL100 were used in tablets prepared by direct compression. The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, compressibility index, total porosity and drug content. The tablets were subjected to various tests for physical parameters such as thickness, hardness and friability, and in vitro release studies. The in vitro dissolution study was carried out for 12 hours using United States Pharmacopoeia (USP) paddle-type dissolution apparatus (Apparatus 2) in phosphate buffer (pH 6.8). The results of dissolution studies indicated that formulations containing Methocel K100 MCR showed better dissolution properties compared to formulaitons containing Methocel K15 MCR.It was found that Hydrophilic polymers showed better released profile than the hydrophobic polymers.

"Sinopsis" puede pertenecer a otra edición de este libro.

Acerca del autor

Dewan Taslima Akhter has obtained her BPharm (Hons.) and MS degree from Jahangirnagar University. Naz H. Huda is graduated from Khulna University and obtained MS degree from United Kingdom. Tajnin Ahmed has obtained her M.Pharm degree from USTC. Authors are Pharmacists and currently working in Department of Pharmacy, Stamford University Bangladesh.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
LAP Lambert Academic Publishing
Año de publicación
2012
Idioma
Inglés
ISBN 10 
3847346067
ISBN 13 
9783847346067
Encuadernación
Tapa blanda
Número de páginas
140
Contacto del fabricante
no disponible
Persona responsable
no disponible