Prodrug Designing of NSAIDs: “Design, Synthesis and Biological Screening of Carrier Linked Prodrugs of Potent NSAIDs”

 
9783843370578: Prodrug Designing of NSAIDs: “Design, Synthesis and Biological Screening of Carrier Linked Prodrugs of Potent NSAIDs”

Separation of therapeutic effects from toxicity is a valuable goal in the drug development process. Prodrug design is a part of the general drug discovery process, in which a unique combination of therapeutically active substances is observed to have desirable pharmacological effects. In human therapy prodrug designing has given successful results in overcoming undesirable properties like absorption, nonspecificity, and poor bioavailability and GIT toxicity. Prodrug design is opening new doors in the challenging field of drug discovery, revolutionizing the art of Drug development.In this dissertation work, Synthesis of amide prodrugs of Niflumic acid and Ketoprofen with Glucosamine was achieved in good yields by a simple technique.Here prodrug approach has been successfully applied in attaining the goal of minimized gastrointestinal toxicity without loss of desired anti-inflammatory activities of the drug.

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About the Author:

Ms. Smita Patil has been working as Asst. Professor in Pharmaceutical Chemistry Department of Shree Santkrupa College of Pharmacy, Ghogaon-Karad. She has 2.2 years experience. She has completed M.Pharmacy from Shivaji University, Kolhapur. She has 6 publications which includes research and review papers in National and International journals.

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Smita Patil
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ISBN 10: 3843370575 ISBN 13: 9783843370578
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Descripción LAP Lambert Academic Publishing 2012-09-12, 2012. paperback. Estado de conservación: New. Nº de ref. de la librería 9783843370578

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Patil, Smita
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Descripción LAP Lambert Academic Publishing, 2016. Paperback. Estado de conservación: New. PRINT ON DEMAND Book; New; Publication Year 2016; Not Signed; Fast Shipping from the UK. No. book. Nº de ref. de la librería ria9783843370578_lsuk

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Descripción Estado de conservación: New. Publisher/Verlag: LAP Lambert Academic Publishing | Design, Synthesis and Biological Screening of Carrier Linked Prodrugs of Potent NSAIDs | Separation of therapeutic effects from toxicity is a valuable goal in the drug development process. Prodrug design is a part of the general drug discovery process, in which a unique combination of therapeutically active substances is observed to have desirable pharmacological effects. In human therapy prodrug designing has given successful results in overcoming undesirable properties like absorption, nonspecificity, and poor bioavailability and GIT toxicity. Prodrug design is opening new doors in the challenging field of drug discovery, revolutionizing the art of Drug development.In this dissertation work, Synthesis of amide prodrugs of Niflumic acid and Ketoprofen with Glucosamine was achieved in good yields by a simple technique.Here prodrug approach has been successfully applied in attaining the goal of minimized gastrointestinal toxicity without loss of desired anti-inflammatory activities of the drug. | Format: Paperback | Language/Sprache: english | 104 pp. Nº de ref. de la librería K9783843370578

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Descripción LAP Lambert Academic Publishing, 2012. Estado de conservación: New. This item is printed on demand for shipment within 3 working days. Nº de ref. de la librería KP9783843370578

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Descripción LAP Lambert Academic Publishing Sep 2012, 2012. Taschenbuch. Estado de conservación: Neu. Neuware - Separation of therapeutic effects from toxicity is a valuable goal in the drug development process. Prodrug design is a part of the general drug discovery process, in which a unique combination of therapeutically active substances is observed to have desirable pharmacological effects. In human therapy prodrug designing has given successful results in overcoming undesirable properties like absorption, nonspecificity, and poor bioavailability and GIT toxicity. Prodrug design is opening new doors in the challenging field of drug discovery, revolutionizing the art of Drug development.In this dissertation work, Synthesis of amide prodrugs of Niflumic acid and Ketoprofen with Glucosamine was achieved in good yields by a simple technique.Here prodrug approach has been successfully applied in attaining the goal of minimized gastrointestinal toxicity without loss of desired anti-inflammatory activities of the drug. 104 pp. Englisch. Nº de ref. de la librería 9783843370578

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Smita Patil
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Descripción LAP Lambert Academic Publishing Sep 2012, 2012. Taschenbuch. Estado de conservación: Neu. Neuware - Separation of therapeutic effects from toxicity is a valuable goal in the drug development process. Prodrug design is a part of the general drug discovery process, in which a unique combination of therapeutically active substances is observed to have desirable pharmacological effects. In human therapy prodrug designing has given successful results in overcoming undesirable properties like absorption, nonspecificity, and poor bioavailability and GIT toxicity. Prodrug design is opening new doors in the challenging field of drug discovery, revolutionizing the art of Drug development.In this dissertation work, Synthesis of amide prodrugs of Niflumic acid and Ketoprofen with Glucosamine was achieved in good yields by a simple technique.Here prodrug approach has been successfully applied in attaining the goal of minimized gastrointestinal toxicity without loss of desired anti-inflammatory activities of the drug. 104 pp. Englisch. Nº de ref. de la librería 9783843370578

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Smita Patil, Dr Pramod Shirote, Rajendra Doijad
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Descripción LAP Lambert Academic Publishing, Germany, 2012. Paperback. Estado de conservación: New. Aufl.. Language: English . Brand New Book ***** Print on Demand *****.Separation of therapeutic effects from toxicity is a valuable goal in the drug development process. Prodrug design is a part of the general drug discovery process, in which a unique combination of therapeutically active substances is observed to have desirable pharmacological effects. In human therapy prodrug designing has given successful results in overcoming undesirable properties like absorption, nonspecificity, and poor bioavailability and GIT toxicity. Prodrug design is opening new doors in the challenging field of drug discovery, revolutionizing the art of Drug development.In this dissertation work, Synthesis of amide prodrugs of Niflumic acid and Ketoprofen with Glucosamine was achieved in good yields by a simple technique.Here prodrug approach has been successfully applied in attaining the goal of minimized gastrointestinal toxicity without loss of desired anti-inflammatory activities of the drug. Nº de ref. de la librería AAV9783843370578

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