Not much research has been done on the regulation of post-transcriptional events, much more is known about transcription. This book illustrates how hormones may influence post-transcriptional nuclear events and that some post-transcriptional modification is a requirement for the expression and function of most higher eukaryotic genes. Topics such as the regulation of pre-mRNA splicing by hormonal signals and tissue-specific mechanisms, pre-mRNA processing during spermatogenesis, to the link between the cell cycle and splicing, the role of phosphorylation and dephosphorylation in the function of the basal splicing machinery, RNA editing, the neuroendocrine regulation of polyadenylation all contribute to make up this volume. If you are an endocrinologist searching for interesting and important answers unearthed by RNA experiments, this book provides them.
"Sinopsis" puede pertenecer a otra edición de este libro.
Not much research has been done on the regulation of post-transcriptional events, much more is known about transcription. This book illustrates how hormones may influence post-transcriptional nuclear events and that some post-transcriptional modification is a requirement for the expression and function of most higher eukaryotic genes. Topics such as the regulation of pre-mRNA splicing by hormonal signals and tissue-specific mechanisms, pre-mRNA processing during spermatogenesis, to the link between the cell cycle and splicing, the role of phosphorylation and dephosphorylation in the function of the basal splicing machinery, RNA editing, the neuroendocrine regulation of polyadenylation all contribute to make up this volume. If you are an endocrinologist searching for interesting and important answers unearthed by RNA experiments, this book provides them.
It is well established that hormones signal to the cell nucleus. However, much research has focused on the transcriptional effects of these external signals. This book illustrates that hormones may also influence post-transcriptional nuclear events. Topics include: the regulation of pre-mRNA splicing by hormonal signals, focusing on the insulin receptor pre-mRNA; calcitonin/CGRP pre-mRNA as the subject of the study of tissue-specific mechanisms; and the extensive repertoire of variant mRNA processing seen during spermatogenesis.
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Hardcover. Condición: Very Good. 8vo, hardcover. No dj. Vg+ condition. Prev. owner's name-labels neatly removed from endpaper; contents bright, crisp & clean, unread. x, 145 p., illus. (some color). Nº de ref. del artículo: 1090610.54
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