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Normal and Binding Mode Analysis of Breast Cancer Resistance Protein: Structural Bioinformatics of BCRP - Tapa blanda
Sinopsis
Breast Cancer Resistance Protein (BCRP) is a membrane-associated protein and a member of the the super family of ATP-binding cassette (ABC) transporters known to confer multidrug resistance (MDR) to a number of important anticancer agent and play an important function in governing drug absorption. This book deals about the development of homology model of BCRP and its correspondence with experimentally known topology. This study also helped to understand the protein dynamics of BCRP through coarse-grained normal mode analysis. Structural analysis of substrate specificity bestowed by specific amino acids and its interaction with various synthetic and natural compounds provided clues of developing an efficient inhibitor.
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Reseña del editor
Breast Cancer Resistance Protein (BCRP) is a membrane-associated protein and a member of the the super family of ATP-binding cassette (ABC) transporters known to confer multidrug resistance (MDR) to a number of important anticancer agent and play an important function in governing drug absorption. This book deals about the development of homology model of BCRP and its correspondence with experimentally known topology. This study also helped to understand the protein dynamics of BCRP through coarse-grained normal mode analysis. Structural analysis of substrate specificity bestowed by specific amino acids and its interaction with various synthetic and natural compounds provided clues of developing an efficient inhibitor.
Biografía del autor
S. Prasanth Kumar, a budding researcher in Department of Bioinformatics, Gujarat University. A recipient of DST INSPIRE fellowship from Ministry of Science and Technology, Government of India. He has been awarded Young Scientist Award twice. He's actively involved in research areas: molecular modeling, structural bioinformatics & sequence analysis.
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Normal and Binding Mode Analysis of Breast Cancer Resistance Protein : Structural Bioinformatics of BCRP
Publicado por
LAP Lambert Academic Publishing, 2012
ISBN 10: 3659153125
ISBN 13: 9783659153129
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Tapa blanda
Librería: Buchpark, Trebbin, Alemania
Calificación del vendedor: 5 de 5 estrellas
Condición: Hervorragend. Zustand: Hervorragend | Seiten: 104 | Sprache: Englisch | Produktart: Bücher. Nº de ref. del artículo: 22559605/1
Cantidad disponible: 1 disponibles
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Normal and Binding Mode Analysis of Breast Cancer Resistance Protein
Publicado por
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659153125
ISBN 13: 9783659153129
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Librería: moluna, Greven, Alemania
Calificación del vendedor: 5 de 5 estrellas
Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kumar PrasanthS. Prasanth Kumar, a budding researcher in Department of Bioinformatics, Gujarat University. A recipient of DST INSPIRE fellowship from Ministry of Science and Technology, Government of India. He has been awarded Young . Nº de ref. del artículo: 5135353
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Imagen de archivo
Normal and Binding Mode Analysis of Breast Cancer Resistance Protein: Structural Bioinformatics of BCRP
Publicado por
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659153125
ISBN 13: 9783659153129
Antiguo o usado
paperback
Librería: Mispah books, Redhill, SURRE, Reino Unido
Calificación del vendedor: 4 de 5 estrellas
paperback. Condición: Like New. Like New. book. Nº de ref. del artículo: ERICA80036591531256
Cantidad disponible: 1 disponibles