Contrast Media: Safety Issues and ESUR Guidelines (Medical Radiology)

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9783642091889: Contrast Media: Safety Issues and ESUR Guidelines (Medical Radiology)

Two years only after the publication of the ? rst edition of “Contrast media – Safety issues and ESUR guidelines” in our book series Medical Radiology in 2006, it appeared that a second edition was urgently needed. The ? rst edition was indeed an exceptional success with our readership and sold out rapidly, but moreover the safety of MR contrast media urgently required a reappraisal after the publication of a new and dramatic adverse reaction to some of the gadolini- based agents: the so called NSF syndrome. I am very much indebted to Professor Henrik S. Thomsen and his academic colleagues from the ESUR Contrast Medium Safety Committee for accepting the task to prepare a second edition of their remarkable book.Within a record short period of time they have been able to complete this fully revised new volume. It offers to the readers a comprehensive overview of all problems related to the use of contrast media in modern radiology and of our latest knowledge and insights in the mechanisms of adverse reactions related to contrast media. It answers all questions that radiologists and referring physicians are confronted with in their daily practice when they consider the administration of these agents to their patients.

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From the Back Cover:

In 1994 the European Society of Urogenital Radiology (ESUR) set up a committee to consider the safety of contrast media used for diagnostic imaging. Subsequently the committee questioned members, reviewed the literature, proposed guidelines and discussed these proposals with participants at the annual symposia of the society. The end result of this work was the successful first edition of this book, published in 2006. This second edition not only updates the previous edition, but also contains some completely new chapters, for example on gadolinium-based contrast agents, meta-analyses in contrast media research and various regulatory issues.

Comprehensive consideration is given to the many different safety issues relating to iodinated, MR, ultrasound and barium contrast media. The text includes chapters on both acute and delayed non-renal adverse reactions and on renal adverse reactions. All those questions frequently raised in radiological practice are addressed, and the well-known ESUR guidelines on contrast media are included. This book, presented in a handy, easy to use format, provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.

About the Author:

Short CURRICULUM VITAE for

HENRIK S. THOMSEN

Born: April 29th 1953

M.D.: University of Copenhagen, June 1979

Dr. Med. (dissertation): University of Copenhagen November 1984

Certified Radiologist: April 1993 (National Health Authorities)

Consultant: April 1996, Department of Diagnostic Radiology, Copenhagen University Hospital at Herlev

Chair: January 2002-2008, Department of Diagnostic Radiology, Copenhagen University Hospital at Herlev

Professor: April 1999, Radiology, University of Copenhagen

Director: 2000, Department of Diagnostic Sciences, Faculty of Health Sciences, University of Copenhagen (renominated for 2007-2012)

Research: Author or co-author of approx. 340 manuscripts (original paper, reviews, book chapters) mainly dealing with radiological topics within the fields of uroradiology, muscleskeletal radiology, contrast media et c.

Editor: Member of the editorial board of 4 international journals (Abdominal Imaging, European Radiology, Academic Radiology, Acta Radiologica); has edited in cooperation with colleagues 8 books in English. Sole editor of one book: Contrast Media: Safety issues and ESUR Guidelines. Guest editor of two issues of Abdominal imaging (2003 & 2006).

Referee: European Journal of Radiology, Scandinavian Journal of Clinical and Laboratory Investigations, Acta Radiologica, Acta Oncologica, Current Opinion in Radiology (USA), Pharmacology & Toxicology, Investigative Radiology (USA), CardioVascular and Interventional Radiology, Annals of Medicine, Academic Radiology (USA), Kidney International (USA), Journal of Clinical Ultrasonography (USA), British Journal of Radiology, European Radiology, Lancet, American Journal of Kidney Diseases, New England Journal of Medicine, Nephrology Dialysis Transplantation, American Journal of Kidney Diseases. Has evaluated > 200 publications.

Advisor: Main advisor for 10 PhD-students

Evaluation: Dissertations and PhD on behalf of University of Copenhagen, University of Southern Denmark, University of Århus, University of Mamö.

Appointment (committee member) of professors and lecturers: University of California Los Angeles, University of Alabama Birmingham, University of Manchester, UK, University of Sheffield, UK, University of Copenhagen, Yale University.

Congresses: Member of organization and/or program committee at more than 20 international congresses and symposia (e.g. European Congress of Radiology, European Symposia on Urogenital Radiology, Radionuclides in Nephro-urology, Mangement in Radiology, Contrast Media Research)

ESUR Contrast Media Safety Committee: Chairman since 1996

ECR Evaluation Committee: Chairman 1993-2002

Committes: ECR Urogential 1995-2001

ECR Contrast Media 2007-2008

Management in Radiology 2003-

ISMRM Committee of NSF 2007-

ESMRMB Safety Committee 2007-

ESUR: Secretary 1990-1996

President-Elect 1996-1998

President 1998-2000

CMR: Convenor 2007-2009

Awards President's AWARD, Society for Uroradiology, September 1990, for best scientific presentation.

December 1990, Jytte Mommsen, født Købler's legat til fremme af den lægevidenskabelige forskning af nyresygdomme.

April 1992 Eyvind Mosekildes Rejselegat, Danish Society of Radiology

Price for cooperation with industry 2004, Copenhagen County

March 2004, Ulrik Brinch og hustru Marie Brinchs legat, (Technical University of Denmark).

Honorary member European Society of Urogenital Radiology

Pacific Northwestern Radiological Society

Member of: The Danish Society of Nephrology

The Danish Society of Clinical Physiology and Nuclear Medicine

Danish Society of Uroradiology

Danish Society for GCP ('Good Clinical Practice')

Society of Uroradiology (USA)

Danish Society of Radiology

Radiological Society of North America (USA)

European Congress of Radiology (Austria)

European Society for Magnetic Resonance in Medicine and Biology

 

Publications:

  1. Thomsen HS, Bonnevie A, Thomsen G. Pleuraforkalkninger - Asbestudsættelse? Ugeskr Læger 1977; 139: 2777-2780.
  2. Thomsen HS, Gottlieb J, Madsen JK, Rasmussen SG, Jensen KB, Christensen JJ, Christensen V: Rutinemæssig røntgenundersøgelse af thorax inden kirurgiske indgreb i universel anæstesi. Ugeskr Læger 1978; 140: 765-768.
  3. Thomsen HS, Dorph S. Pyelorenal backflow during retrograde pyelography after renal transplantation. Scand J Urol Nephrol 1978; 12: 175-179.
  4. Thomsen HS, Dorph S, Olsen S. Pyelorenal backflow in normal and ischemic rabbit kidneys. Invest Radiol 1981; 16: 206-214.
  5. Thomsen HS, Dorph S. Pyelorenal backflow during retrograde pyelography in adult patients. Scand J Urol Nephrol 1981; 15: 65-68.
  6. Thomsen HS, Dorph S, Olsen S. Pyelorenal backflow: Experimental studies in rabbits. - Evalueret abstract. Amer J Roentgenol 1981; 137: 198.
  7. Thomsen HS, Madsen JK, Thaysen JH, Damgaard Pedersen K. Volume of polycystic kidneys during reduction of renal function. Urol Radiol 1981; 3: 85-89. Abstr.: Radiology 1982; 144: 720.
  8. Thomsen HS, Dorph S, Olsen S. Pyelorenal backflow in rabbits following clamping of the renal vein and artery. Radiologic and microscopic investigation. Acta Radiol Diagn 1982; 23: 143-148.
  9. Thomsen HS, Taylor Jr. A. Evaluation of renal ischemia with 99mTc-pyrophosphate. Eur J Nucl Med 1982; 7: 147-149. Abstr.: Radiology 1982; 145: 590.
  10. Thomsen HS, Larsen S, Talner LB. Pyelorenal backflow during retrograde pyelography in normal and ischemic porcine kidneys. A radiologic and pathoanatomic study. Eur Urol 1982; 8: 291-297.
  11. Thomsen HS. Rapport fra klinisk fysiologisk udvalg. DBCG's informationsblad 1982; 9: 12-13.
  12. Thomsen HS, Talner LB, Higgins CB. Intrarenal backflow during retrograde pyelography with graded intrapelvic pressure. Invest Radiol 1982; 17: 593-603.
  13. Thaysen JH, Thomsen HS. Involution of polycystic kidneys during replacement therapy of terminal renal failure. Acta Med Scand 1982; 212: 389-394.
  14. Thomsen HS, Larsen S, Talner LB. Papillary morphology in adult human kidneys and in baby and adult pig kidneys. Eur Urol 1983; 9: 170-180.
  15. Thomsen HS, Hartelius H, Jensen R, Flindt-Nielsen N, Ohlhues L. Excretory urography with glucagon: A randomized trial. Radiology 1983; 147: 335-338.
  16. Thomsen HS, Larsen S. Intrarenal backflow during retrograde pyelography with graded intrapelvic pressure. A pathoanatomic study. Acta path microbiol immunol scand Sect A 1983; 91: 245-252.
  17. Thomsen HS. Pressures during retrograde pyelography. Acta Radiol Diagn 1983; 24: 171-175.
  18. Thomsen HS. Refluxnefropati på basis af vesikoureteral refluks. (oversigtsartikel). Ugeskr Læger 1983; 145: 3334-3338.
  19. Thomsen HS, Larsen S. Refluksnefropati. (kasuistik). Ugeskr Læger 1983; 145: 3339-3340.
  20. Thomsen HS, Dorph S, Larsen S, Talner LB. Intrarenal backflow and renal perfusion during increased intrapelvic pressure in excised porcine kidneys. Acta Radiol Diagn 1983; 24: 327-336.
  21. Dorph S, Mygind T, Thomsen HS. The early nephrogram during urography in kidney transplants. - Evalueret abstract. Amer J Roentgenol 1984; 142: 239.
  22. Thomsen HS. Excretory urography with glucagon: A randomized trial. (specielt udarbejdet abstract af artikel 15 efter anmodning). Postgraduate Radiol 1984; 4: 206-207.
  23. Thomsen HS, Løkkegaard H, Munck O. Evaluation of kidney grafts with 99mTc-methylene diphosphonate within 36 hours after transplantation: A marker of ischemic damage. Eur J Nucl Med 1984; 9: 115-120.
  24. Thomsen HS. Intrarenal backflow during retrograde pyelography following kidney transplantation. Acta Radiol Diagn 1984; 25: 113-120.
  25. Thomsen HS, Munck O, Andersen KW. Værdien af rutinemæssig knoglescintigrafi ved primær operabel cancer mammae. Ugeskr Læger 1984; 146: 1915-1918.
  26. Thomsen HS, Lund JO, Munck O, Andersen KW, Støckel M, Rossing N. Bone metastases in primary operabel breast cancer. The role of serial scintigraphy. Eur J Cancer Clin Oncol 1984; 8: 1019-1023.
  27. Thomsen HS. PYELORENAL BACKFLOW. CLINICAL AND EXPERIMENTAL INVESTIGATIONS. RADIOLOGIC, NUCLEAR MEDICAL AND PATHOANATOMIC STUDIES. (disputats). Lægeforeningens Forlag, København 1984; 1-24. Dan Med Bull 1984; 31: 438-457.
  28. Thomsen HS. Pyelorenal backflow. Clinical and experimental investigations. Radiologic, nuclear medical and pathoanatomic studies. (specielt udarbejdet abstract af artikel 27 efter anmodning). Ugeskr Læger 1984; 146: 3379-3380.
  29. Thomsen HS, Dorph S, Mygind T. Subtraction nephrotomography during urography of transplanted kidneys. Acta Radiol Diagn 1984; 25: 495-500.
  30. Munck O, Thomsen HS, Lund JO, Støckel M, Andersen KW, Rossing N. Bone metastases in primary operable breast cancer. The role of serial scintigraphy. I: Schmidt HAE, Varumo DE (eds.) Nuklearmedizin (Nuclear Medicine in Research and Practice). Schattauer Verlag, Stuttgart; 1984: 536-539.
  31. Thomsen HS. Vesioureteral reflux and reflux nephropathy. (oversigtsartikel). Acta Radiol Diagn 1985; 26: 3-13.
  32. Thomsen HS. Filling of the central intrarenal veins during retrograde pyelography following a recent kidney transplantation (kasuistik). Acta Radiol Diagn 1985; 26: 206-211.
  33. Thaysen JH, Thomsen HS, Sass A, Kristensen JK.Volume changes of polycystic kidneys during chronic dialysis and after renal transplantation. Acta Med Scand 1985; 217: 197-204.
  34. Thomsen HS, Dorph S, Mygind T, Holm HH, Munck O, Damgaard Pedersen K. The transplanted kidney. Diagnostic and interventional radiology (oversigtsartikel). Acta Radiol Diagn 1985; 26: 353-367.
  35. Thomsen HS, Rygaard H, Strandberg C. Micturating cystourethrography and vesicoureteral reflux. Variations in technique. Eur J Radiol 1985; 5: 318-320.
  36. Thomsen HS. Vesicoureteral reflux and reflux nephropathy. (specielt udarbejdet abstract af artikel 31 efter anmodning). Postgraduate Radiol 1986; 6: 139-140.
  37. Vyberg M, Miskowiak J, Nielsen SL, Fahrenkrug L, Thomsen HS. Cecal angiodysplasia localized by 99mTechnetium blood pool scintigraphy and specimen venography. (kasuistik). Cardiovasc Interv Radiol 1986; 9: 28-32.
  38. Zobbe VB, Rygaard H, Rasmussen D, Strandberg C, Krause S, Hartsen SH, Thomsen HS. Glucagon in acute ureteral colic. A randomized trial. Eur Urol 1986; 12: 28-31.
  39. Thomsen HS, Dorph S. Caliceal clubbing and adjacent parenchymal scarring (always reflux nephropathy?) as a cause of end-stage renal failure. Acta Radiol Diagn 1986; 27: 705-710.
  40. Thomsen HS, Munck O, Løkkegaard H. 90-min 99mTc-MDP scintigraphy and 131I-Hippuran renography in recently allotransplanted kidneys: Evaluation of renal ischemia. Eur J Nucl Med 1986; 12: 110-114.
  41. Thomsen HS, Nielsen SL, Larsen S, Løkkegaard H. Renography and biopsy-verified acute rejection in renal allotransplanted patients receiving cyclosporin A. Eur J Nucl Med 1987; 12: 473-476.
  42. Thomsen HS. Opdigtet videnskabeligt arbejde. (leder). Ugeskr Læger 1987; 149: 539-540.
  43. Thomsen HS, Munck O. Use of 99Tcm radionuclides to show nephrotoxicity of cyclosporin A in transplanted kidneys. Acta Radiol 1987; 28: 59-61.
  44. Thomsen HS, Dorph S. The upper urinary tract. Pyelography and interventional procedures. (oversigtsartikel). Acta Radiol 1987; 28: 129-137.
  45. Thomsen HS, Munck O. Nephrotoxicity of ciclosporin in transplanted kidneys demonstrated with 99mTc perfusion studies. Contrib Nephrol 1987; 56: 159-162.
  46. Nielsen SL, Hvid-Jacobsen K, Thomsen HS, Munck O. Renal washout and vascular resistance (kasuistik). Eur J Nucl 1987; 12: 629-630.
  47. Thomsen HS, Hvid-Jacobsen K, Pedersen T, Nielsen SL. Radionuclide techniques in renal/renovascular hypertension. (oversigtsartikel). IM-Internal Medicine for the Specialist 1987; 8: 231-246.
  48. Munck O, Thomsen HS. Nephrotoxicity of cyclosporin A in transplanted kidneys demonstrated with Tc-99m perfusion technique. In: Schmidt HAE, Emrich D (eds.). Nuklearmedizin (Clinical Demands on Nuclear Medicine). Schattauer Verlag, Stuttgart; 1987: 287-289.
  49. Thomsen HS, Rasmussen D, Munck O, Dombernowsky P. Knoglescintigrafi ved nydiagnosticeret cancer mammae; en overflødig rutine? Ugeskr Læger 1987; 149: 1453-1455.
  50. Thomsen HS, Dombernowsky P. Knogleskintigrafi ved cancer mammae. (leder). Ugeskr Læger 1987; 149: 1480.
  51. Thomsen HS, Rygaard H, Nielsen SL, Larsen S, Løkkegaard H. Angiography in non-functioning renal allografts receiving cyclosporin A. Acta Radiol 1987; 28: 313-317.
  52. Thomsen HS, Løkkegaard H, Munck O. Influence of normal central venous pressure on onset of function in renal allografts. Scand J Urol Nephrol 1987; 21: 143-145.
  53. Thomsen HS, Hvid-Jacobsen K, Nielsen SL. Alternating use of 123I and 131I hippuran for routine postoperative monitoring of transplanted kidneys is impracticable. Acta Radiol 1987; 28: 365-367.
  54. Thomsen HS, Rasmussen D, Munck O, Lund JO, Nielsen VG, Terkildsen T, Dombernowsky P, Andersen KW. Bone metastases in primary operable breast cancer. The role of a yearly scintigraphy. Eur J Cancer Clin Oncol 1987; 11: 779-781.
  55. Skaarup P, Thomsen HS. Urinary protein profiles following urography with iothalamate: A preliminary report. Acta Radiol 1987; 28: 335-338.
  56. Thomsen HS, Nielsen SL, Munck O. Prægraduat ikke obligatorisk undervisning i specialer uden eksamen. Klinisk fysiologi og nuklearmedicin som eksempel. Ugeskr Læger 1987; 149: 3014-3015.
  57. Thomsen HS. Knoglescintigrafi ved cancer mammae. DBCG's informationsblad 1987; 19: 24-27.
  58. Thomsen HS, Hvid-Jacobsen K, Meyhoff H-H, Nielsen SL. Combination of DMSA scintigraphy and hippuran renography in unilateral obstructive nephropathy: Improved prediction of recovery after intervention. Acta Radiol 1987; 28: 653-655.
  59. Hvid-Jacobsen K, Nielsen SL, Jensen VJ, Thomsen HS. Demonstration of the thoracic duct by 123I heptadecanoic acid. (kasuistik). Acta Radiol 1987; 28: 783-784.
  60. Strandberg C, Falkenløve P, Dorph S, Jakobsen S, Thomsen HS. Effect of glucagon-(1-21)-peptide on gastroduodenal motility during upper gastrointestinal examination. Randomized trials. Acta Radiol 1988; 29: 49-52.
  61. Thomsen HS, Rasmussen K, Burcharth F, Nielsen SL. Monitoring of pancreatic graft perfusion by first passage radionuclide angiography. Acta Radiol 1988; 29: 138-140.
  62. Thomsen HS, Dorph S, My...

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