Parameter estimation of Michaelis-Menten kinetics: Comparison between experimental design methodologies and equidistant sampling using genetic algorithms - Tapa blanda

Ataíde, Filipe; Hitzmann, Bernd

 
9783639253344: Parameter estimation of Michaelis-Menten kinetics: Comparison between experimental design methodologies and equidistant sampling using genetic algorithms
Tapa blanda
ISBN 10: 3639253345 ISBN 13: 9783639253344
Editorial: VDM Verlag Dr. Müller, 2010

Sinopsis

The main objective of this work was to investigate the application of experimental design techniques for the identification of Michaelis-Menten kinetic parameters. More specifically, this study attempts to elucidate the relative advantages/disadvantages of employing complex experimental design techniques in relation to equidistant sampling when applied to different reactor operation modes. All studies were supported by simulation data of a generic enzymatic process that obeys to the Michaelis-Menten kinetic equation. Different aspects were investigated, such as the influence of different reactor operation modes (batch, fed-batch with pulsewise feeding and fed- batch with continuous feeding) and the experimental design optimality criteria on the effectiveness of kinetic parameters identification.

"Sinopsis" puede pertenecer a otra edición de este libro.

Reseña del editor

The main objective of this work was to investigate the application of experimental design techniques for the identification of Michaelis-Menten kinetic parameters. More specifically, this study attempts to elucidate the relative advantages/disadvantages of employing complex experimental design techniques in relation to equidistant sampling when applied to different reactor operation modes. All studies were supported by simulation data of a generic enzymatic process that obeys to the Michaelis-Menten kinetic equation. Different aspects were investigated, such as the influence of different reactor operation modes (batch, fed-batch with pulsewise feeding and fed- batch with continuous feeding) and the experimental design optimality criteria on the effectiveness of kinetic parameters identification.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
VDM Verlag Dr. Müller
Año de publicación
2010
Idioma
Inglés
ISBN 10 
3639253345
ISBN 13 
9783639253344
Encuadernación
Tapa blanda
Número de páginas
88
Contacto del fabricante
no disponible
Persona responsable
no disponible