Microfluidic Technologies for Single-Cell Analysis: Creating uniform cellular microenvironments for fast timescale measurements - Tapa blanda

Di Carlo, Dino

 
9783639139518: Microfluidic Technologies for Single-Cell Analysis: Creating uniform cellular microenvironments for fast timescale measurements
Tapa blanda
ISBN 10: 3639139518 ISBN 13: 9783639139518
Editorial: VDM Verlag, 2009

Sinopsis

Analysis of single cells allows a complete understanding of the heterogeneity that is present in cell behavior and function. Current single-cell analysis methods provide high-throughput information about labeled biomolecules within cells, but often cannot follow the dynamic processes occurring in signaling pathways. New microfluidic methods have separately allowed assays of fast timescale responses or creation of uniform environments to study cell behavior in a more quantitative manner. This book focuses on microfluidic hydrodynamic trapping techniques that aid in both fast timescale measurements and uniform environmental control in a single platform. Example applications for fast timescale analysis of pore-forming toxin insertion into membranes and assays of single-cell enzyme content will be presented. The book would be of interest to analytical chemists, engineers, and biologists developing platforms to study single-cell behavior. Also, biologists looking for tools to study cells of interest with statistical accuracy would find the book most helpful.

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Reseña del editor

Analysis of single cells allows a complete understanding of the heterogeneity that is present in cell behavior and function. Current single-cell analysis methods provide high-throughput information about labeled biomolecules within cells, but often cannot follow the dynamic processes occurring in signaling pathways. New microfluidic methods have separately allowed assays of fast timescale responses or creation of uniform environments to study cell behavior in a more quantitative manner. This book focuses on microfluidic hydrodynamic trapping techniques that aid in both fast timescale measurements and uniform environmental control in a single platform. Example applications for fast timescale analysis of pore-forming toxin insertion into membranes and assays of single-cell enzyme content will be presented. The book would be of interest to analytical chemists, engineers, and biologists developing platforms to study single-cell behavior. Also, biologists looking for tools to study cells of interest with statistical accuracy would find the book most helpful.

Biografía del autor

Dino Di Carlo is an Assistant Professor of Bioengineering at UCLA. He received his B.S. and Ph.D. in Bioengineering from UC Berkeley and San Francisco. He then conducted postdoctoral studies at Harvard Medical School and MGH. His research focuses on miniaturization technologies for advanced diagnostic and automated single cell analysis systems.

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Editorial
VDM Verlag
Año de publicación
2009
Idioma
Inglés
ISBN 10 
3639139518
ISBN 13 
9783639139518
Encuadernación
Tapa blanda
Número de páginas
116
Contacto del fabricante
no disponible
Persona responsable
no disponible