This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management.
Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks.
In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
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In recent years, great advances in translational research have led to new paradigms in the treatment of cancers of the head and neck. Written by leading international physicians and investigators, this innovative multi-disciplinary book presents the most up-to-date research and clinical approaches. Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease. Complementary to the techniques of surgery, radiotherapy, and systemic treatments, the authors present data on epidemiology, molecular pathology, normal tissue complications, rehabilitation, palliative care, and treatment in the elderly. State-of-the-art functional imaging is elucidated; and the latest developments in high precision techniques in irradiation, sequencing of chemo- and radiotherapy, as well as the integration of biomolecular therapies into cytotoxic treatments are explored.About the Author:
After obtaining his degree in Radio-Oncology at the University of Liege, Belgium, Jacques Bernier completed his training at the MD Anderson Cancer Center, Houston, and the Curie Institute, Paris. In 2006 he joined the Swiss Genolier Medical Network, where since then he has been chairing the Radio-Oncology Department. Throughout most of his career, Jacques Bernier has been heavily involved with translational and clinical research. From 2000 to 2006 Jacques Bernier was Chairman of the Head and Neck Group of the EORTC. He currently serves as an Editorial Board member of various international peer-reviewed journals, including “Journal of Clinical Oncology”. He is an Associate Editor of “Annals of Oncology” (since 2010), and “Oral Oncology” (since January 2011). A Course Director at the European School of Oncology since 1990, Jacques Bernier is also the Chairman of the International Conference on Translational Research in Radio-Oncology - ICTR, organized every three years in Switzerland. He serves as a regular member of advisory boards for many pharmaceutical companies. He is President of the Foundation for the Advancement of Radiation Oncology – FARO, in Geneva, member of the Executive Board of Euro-Asian Society of Mastology - EURAMA, Board of Trustees of “Science for Peace” and Scientific Committee of the “Umberto Veronesi Foundation” in Milan.
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