Páginas:106Géneros:12:MFG:PhysiologySinopsis:Hypertensionisdefinedbyanincreaseinsystemicbloodpressureabovelimitsconsiderednormal,currentlysetat140mmHgforsystolicand90mmHgfordiastolicpressure.Assumingcentralvenouspressuretobenearzero,meanarterialpressureisdeterminedbytheproductoftotalperipheralresistanceandcardiacoutput.Inmostcasesofessentialhypertension,aswellasinanimalmodelsofhypertension,cardiacoutputanditsmaindeterminants,strokevolumeandheartrate,arenormal,whereastotalperipheralresistanceisincreased.TotalperipheralresistanceisinfluencedbyanumberoffactorsdescribedbythePoiseuilleslaw,themostsignificantofwhichbyfaristhediameterofbloodvesselsofthearterialtree.Sincebloodvesseldiameterisareflectionofbothvascularstructureandactiveregulationofvasculartonethroughmechanismsofvasoconstrictionandvasodilatation,itisgenerallyconsideredthatalterationsintotalperipheralresistancearedirectlydeterminedbyalterationsinvascularsmoothmusclestructureand/orfunction.Thus,complexbloodpressureregulationsystems,includingrenal,nervous,endocrine,immune,andothers,intheirturninfluencedbygeneticorenvironmentalfactors,convergeuponthesamemolecularmechanismsthatcontrolthestructureandfunctionofvascularsmoothmuscle.Inthiswork,ratherthanprovidingtheexhaustivelistofmodificationsinthebloodpressureregulatingsystemsthatultimatelyaffectthevasculatureinhypertension,wewillfocusonthestructuralandfunctionalalterationsofvascularsmoothmuscleperseduringhypertension._,
"Sinopsis" puede pertenecer a otra edición de este libro.
“...the authors have succeeded in including enough detail that physiologists and pharmacologists at any career stage, researchers of vascular biology and hypertension, students of cardiovascular physiology, even cardiologists interested in vascular biology, will find this short book very useful to acquire an idea of mechanisms that participate in the contribution that vascular smooth muscle in the wall of blood vessels make to elevated blood pressure.” – Ernesto L. Schiffrin, Physician-in-Chief, Sir Mortimer B. Davis-Jewish General Hospital, Montreal
“The book is user-friendly, clearly written and enriched with many useful and informative figures and photographs. I highly recommend this book to all students, researchers and clinicians interested in the vascular biology of hypertension.” – Rhian M. Touyz, President, International Society of Hypertension
“Without a doubt, I would use this text to conduct in-depth discussions on this subject, as well as I will use this material as a source of study for myself. I congratulate the editors for the choice of both authors, who undoubtedly managed to thoroughly review the vascular smooth muscle cell during hypertensive condition.” – Fernanda Giachini Vitorino, Universidade Federal do Mato Grosso
Hypertension is defined by an increase in systemic blood pressure above limits considered normal, currently set at 140 mmHg for systolic and 90 mmHg for diastolic pressure. Assuming central venous pressure to be near zero, mean arterial pressure is determined by the product of total peripheral resistance and cardiac output. In most cases of essential hypertension, as well as in animal models of hypertension, cardiac output and its main determinants, stroke volume and heart rate, are normal, whereas total peripheral resistance is increased. Total peripheral resistance is influenced by a number of factors described by the Poiseuille's law, the most significant of which by far is the diameter of blood vessels of the arterial tree. Since blood vessel diameter is a reflection of both vascular structure and active regulation of vascular tone through mechanisms of vasoconstriction and vasodilatation, it is generally considered that alterations in total peripheral resistance are directly determined by alterations in vascular smooth muscle structure and/or function. Thus, complex blood pressure regulation systems, including renal, nervous, endocrine, immune, and others, in their turn influenced by genetic or environmental factors, converge upon the same molecular mechanisms that control the structure and function of vascular smooth muscle. In this work, rather than providing the exhaustive list of modifications in the blood pressure regulating systems that ultimately affect the vasculature in hypertension, we will focus on the structural and functional alterations of vascular smooth muscle per se during hypertension.
"Sobre este título" puede pertenecer a otra edición de este libro.
EUR 6,59 gastos de envío desde Reino Unido a Estados Unidos de America
Destinos, gastos y plazos de envíoEUR 3,52 gastos de envío en Estados Unidos de America
Destinos, gastos y plazos de envíoLibrería: WorldofBooks, Goring-By-Sea, WS, Reino Unido
Paperback. Condición: Very Good. The book has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged. Nº de ref. del artículo: GOR012700989
Cantidad disponible: 1 disponibles
Librería: Lucky's Textbooks, Dallas, TX, Estados Unidos de America
Condición: New. Nº de ref. del artículo: ABLIING23Mar2811580141988
Cantidad disponible: Más de 20 disponibles
Librería: PBShop.store US, Wood Dale, IL, Estados Unidos de America
PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Nº de ref. del artículo: IQ-9781615046843
Cantidad disponible: 15 disponibles
Librería: PBShop.store UK, Fairford, GLOS, Reino Unido
PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Nº de ref. del artículo: IQ-9781615046843
Cantidad disponible: 15 disponibles
Librería: Chiron Media, Wallingford, Reino Unido
PF. Condición: New. Nº de ref. del artículo: 6666-IUK-9781615046843
Cantidad disponible: 10 disponibles
Librería: Ria Christie Collections, Uxbridge, Reino Unido
Condición: New. In. Nº de ref. del artículo: ria9781615046843_new
Cantidad disponible: Más de 20 disponibles
Librería: Books Puddle, New York, NY, Estados Unidos de America
Condición: New. pp. 106. Nº de ref. del artículo: 26385780579
Cantidad disponible: 4 disponibles
Librería: Revaluation Books, Exeter, Reino Unido
Paperback. Condición: Brand New. 96 pages. 9.25x7.50x0.22 inches. In Stock. Nº de ref. del artículo: x-1615046844
Cantidad disponible: 2 disponibles
Librería: THE SAINT BOOKSTORE, Southport, Reino Unido
Paperback / softback. Condición: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days 525. Nº de ref. del artículo: C9781615046843
Cantidad disponible: Más de 20 disponibles
Librería: Biblios, Frankfurt am main, HESSE, Alemania
Condición: New. PRINT ON DEMAND pp. 106. Nº de ref. del artículo: 18385780585
Cantidad disponible: 4 disponibles