Thyroid Hormone Disruption and Neurodevelopment - Tapa blanda

Sinopsis

Section 1: Disruption of thyroid hormone action at molecular level.- 1 Molecular mechanisms of thyroid hormone action in brain: a general overview.- 2 Deoidinases and brain development.- 3 Disruption of thyroid hormone receptor-mediated action in brain by endocrine disrupting chemicals.- 4 Chemical disruption of deiodinase activities during pregnancy and fetal neurotoxicity.- 5 Effect of maternal/neonatal infection on thyroid hormone-mediated neurodevelopment.- 6 Disruption of feedback regulation of thyroid hormone synthesis/secretion and brain development.- Section 2: Animal models to study thyroid hormone disruption on neurodevelopment.- 7 Animal models to study thyroid hormone action in neurodevelopment.- 8 Thyroid hormone receptor mutation and neurodevelopment.- 9 Pax6 knockout and cerebellar development.- 10 Disruption of auditory function by thyroid hormone receptor mutation.- Section 3 Thyroid hormone disruption and neurodevelopment: human studies.- 11 Maternal hypothyroidism and brain development of newborns.- 12 Congenital hypothyroidism and neurodevelopment.- 13 Iodine deficiency and brain development.- 14 Deficit in thyroid hormone transporters and brain development.- 15 Syndrome of resistance to thyroid hormone and brain development.​

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