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Sinopsis
Praise for the Second Edition:
"... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics
"This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ..." - Journal of the Royal Statistical Society
Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.
Features:
- Compares the relative merits and disadvantages of statistical methods for sample size calculations
- Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages
- Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women's health
- Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches
This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.
"Sinopsis" puede pertenecer a otra edición de este libro.
Acerca del autor
Shein-Chung Chow, PhD, is a professor in the Department of Biostatistics and Bioinformatics at Duke University School of Medicine. Dr. Chow is also an adjunct professor at Duke-National University of Singapore Graduate Medical School, an adjunct professor at North Carolina State University, and founding director of the Global Clinical Trial and Research Center in Tianjin, China. He is editor-in-chief of the Journal of Biopharmaceutical Statistics and editor-in-chief of the Chapman & Hall/CRC Biostatistics Series. He is the author or co-author of more than 250 papers and 24 books, including Adaptive Design Methods in Clinical Trials, Second Edition, Handbook of Adaptive Designs in Pharmaceutical and Clinical Development, and Controversial Statistical Issues in Clinical Trials. A fellow of the ASA and member of the ISI, Dr. Chow has received the ASA Chapter Service Recognition Award, the DIA Outstanding Service Award, and the ICSA Extraordinary Achievement Award.
Dr. Lokhnygina is an Assistant Professor of Biostatistics and Bioinformatics at Duke University and a faculty member at Duke Clinical Research Institute. Her primary research interests are in statistical methods for multicenter clinical trials, particularly in application to cardiovascular and diabetes research.
"Sobre este título" puede pertenecer a otra edición de este libro.
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SAMPLE SIZE CALCULATIONS IN CLINICAL RESEARCH
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CRC Press, Taylor & Francis Group, Boca Raton, 2018
ISBN 10: 1138740985
ISBN 13: 9781138740983
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Hardcover. Condición: Near Fine. 3rd edition. 3rd edition, 2018. Near Fine. 4to., 492 pp., bound in publishers glossy blue paper boards. Very minor signs of shelf wear. Nº de ref. del artículo: 29732
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Sample Size Calculations in Clinical Research
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ISBN 10: 1138740985
ISBN 13: 9781138740983
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Sample Size Calculations in Clinical Research
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Sample Size Calculations in Clinical Research (Chapman & Hall/CRC Biostatistics Series)
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Chapman and Hall/CRC, 2017
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ISBN 13: 9781138740983
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Chow, S: Sample Size Calculations in Clinical Research
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Shein-Chung Chow, PhD, is a professor in the Department of Biostatistics and Bioinformatics at Duke University School of Medicine. Dr. Chow is also an adjunct professor at Duke-National University of Singapore Graduate Medical School, an. Nº de ref. del artículo: 595426176
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Sample Size Calculations in Clinical Research
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Sample Size Calculations in Clinical Research
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Taylor & Francis Ltd Aug 2017, 2017
ISBN 10: 1138740985
ISBN 13: 9781138740983
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Praise for the Second Edition:'. this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study.' -Biometrics'This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered .' - Journal of the Royal Statistical SocietySample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.Features:Compares the relative merits and disadvantages of statistical methods for sample size calculationsExplains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stagesPresents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women's healthProvides sample size calculations for dose response studies, microarray studies, and Bayesian approachesThis new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation. 510 pp. Englisch. Nº de ref. del artículo: 9781138740983
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Sample Size Calculations in Clinical Research
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Sample Size Calculations in Clinical Research, Third Edition (Chapman & Hall/CRC Biostatistics Series)
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Taylor & Francis Group, 2017
ISBN 10: 1138740985
ISBN 13: 9781138740983
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Sample Size Calculations in Clinical Research (Chapman & Hall/CRC Biostatistics Series)
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