Antineoplastic Drugs: Organic Syntheses

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9781118892541: Antineoplastic Drugs: Organic Syntheses

The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry.

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1.

Daniel Lednicer
Editorial: John Wiley and Sons Ltd, United States (2015)
ISBN 10: 1118892542 ISBN 13: 9781118892541
Nuevos Tapa dura Primera edición Cantidad: 10
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The Book Depository
(London, Reino Unido)
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Descripción John Wiley and Sons Ltd, United States, 2015. Hardback. Estado de conservación: New. 1. Auflage. Language: English . Brand New Book. The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry. Nº de ref. de la librería AAH9781118892541

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Daniel Lednicer
ISBN 10: 1118892542 ISBN 13: 9781118892541
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Descripción Estado de conservación: New. Nº de ref. de la librería 20396676-n

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Daniel Lednicer
Editorial: John Wiley and Sons Ltd, United States (2015)
ISBN 10: 1118892542 ISBN 13: 9781118892541
Nuevos Tapa dura Primera edición Cantidad: 10
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The Book Depository US
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Descripción John Wiley and Sons Ltd, United States, 2015. Hardback. Estado de conservación: New. 1. Auflage. Language: English . Brand New Book. The past decade has seen a significant increase of research aimed at discovering new drugs for treating cancer, and the increasing number of new antineoplastic drugs approved by regulatory agencies reflects this. Until now, details on the synthesis of these newer agents have been scattered in various journals and in US and European patents. This timely volume deals with the organic chemistry involved in the synthesis of the agents found within antineoplastic drugs, including descriptions of the synthetic schemes for the preparation of over 200 compounds that have been granted non-proprietary names. Compounds are collected in chapters based on the mechanism of action rather than on their chemical structures. Each individual chapter is preceded by a brief description of that mechanism and includes detailed flow charts of the preparation of those compounds accompanied by discussions of the organic chemistry involved in each step. The first half of this volume is dedicated to the syntheses of established chemotherapy drugs. Kinase inhibitors occupy the following chapters with the largest single chapter dealing with the fifty compounds that inhibit tyrosine kinase. This class stands out since over twenty compounds in this group have been approved for treating patients; a rare track record compared to any other class of therapeutic agents. Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations. The book is accessible to advanced undergraduates as well as graduates and researchers as well as those with a thorough grasp of organic chemistry. Nº de ref. de la librería AAH9781118892541

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Daniel Lednicer
Editorial: Wileyand#8211;Blackwell (2015)
ISBN 10: 1118892542 ISBN 13: 9781118892541
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Books2Anywhere
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Descripción Wileyand#8211;Blackwell, 2015. HRD. Estado de conservación: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Nº de ref. de la librería FW-9781118892541

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Daniel Lednicer
Editorial: Wiley 2015-05-01, Chichester, West Sussex (2015)
ISBN 10: 1118892542 ISBN 13: 9781118892541
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Descripción Wiley 2015-05-01, Chichester, West Sussex, 2015. hardback. Estado de conservación: New. Nº de ref. de la librería 9781118892541

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Daniel Lednicer
Editorial: Wiley-Blackwell
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Descripción Wiley-Blackwell. Hardcover. Estado de conservación: New. New copy - Usually dispatched within 2 working days. Nº de ref. de la librería B9781118892541

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Daniel Lednicer (Analytical Bio-Chemistry Laboratories, Inc., Columbia, Missouri)
Editorial: John Wiley and Sons
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Descripción John Wiley and Sons. Estado de conservación: New. Brand New. Nº de ref. de la librería 1118892542

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Daniel Lednicer
Editorial: Wiley (2015)
ISBN 10: 1118892542 ISBN 13: 9781118892541
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Descripción Wiley, 2015. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería M1118892542

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LEDNICER
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Descripción 2015. Hardback. Estado de conservación: NEW. 9781118892541 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE0884850

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Lednicer, Daniel
Editorial: John Wiley & Sons Inc (2015)
ISBN 10: 1118892542 ISBN 13: 9781118892541
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Revaluation Books
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Descripción John Wiley & Sons Inc, 2015. Hardcover. Estado de conservación: Brand New. 1st edition. 232 pages. 9.75x6.75x0.50 inches. In Stock. Nº de ref. de la librería __1118892542

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