Sites of Drug Action in the Human Brain - Tapa dura

Sites of Drug Action in the Human Brain uses the results of recent analyses of the regional brain distribution and binding pattern of drugs in the human brain. This new book specifically addresses drugs of abuse and treats the effects of various drugs on behavior and mood, as well as on metabolism and blood flow in the human brain. It also presents the methodological aspects of investigating the sites of drug action in the human brain.
Because it focuses on the living human brain, this book differs from other books on the subject, which primarily use the results of postmortem studies. Sites of Drug Action in the Human Brain therefore provides valuable information on the clinical aspects of drug intoxification, addiction, and toxicity.

When dealing with drugs which primarily affect behavior, the assumption is that the drugs in question are capable of penetrating the blood brain barrier and interacting directly with the brain. Presumably, different drugs interact with specific sites located in particular brain regions in order to exert their action. In this chapter, we shall provide a concise description of the most common methodologies employed to localize and characterize sites of drug action in the brain.