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Sinopsis
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.
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Críticas
"... this is an excellent, very favourably-priced, all-round toxicology textbook suitable for all those new to the area and also invaluable for those longer in the tooth. Buy it and see for yourself what a great read it is!"
―Paul Baldrick, Covance Laboratories Ltd, UK in BTS Newsletter, Issue 32 in 2008
"Wallace-Hayes has engaged over 90 distinguished investigators to contribute to this new edition. There is also a chapter dedicated to ... Statistics ... the information is presented in a logical sequence and it is an excellent reference source. I would recommend this book to any working one aiming to study in the area of safety sciences and it is a necessity for all those working in this area."
―Shirley Price in BTS Newsletter, Issue 32 in 2008
Reseña del editor
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential.
Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology.
Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.
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Condición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,3450grams, ISBN:9780849337789. Nº de ref. del artículo: 9185756
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Principles and Methods of Toxicology, Fifth Edition
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Condición: acceptable. The book is complete and readable, with all pages and cover intact. Dust jacket, shrink wrap, or boxed set case may be missing. Pages may have light notes, highlighting, or minor water exposure, but nothing that affects readability. May be an ex-library copy and could include library markings or stickers. Nº de ref. del artículo: BSM.RXCH
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Principles and Methods of Toxicology, Fifth Edition
Publicado por
CRC Press (edition 5), 2007
ISBN 10: 084933778X
ISBN 13: 9780849337789
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Hardcover. Condición: Good. 5. It's a preowned item in good condition and includes all the pages. It may have some general signs of wear and tear, such as markings, highlighting, slight damage to the cover, minimal wear to the binding, etc., but they will not affect the overall reading experience. Nº de ref. del artículo: 084933778X-11-1
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Principles and Methods of Toxicology
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CRC Press, Boca Raton, FL, 2008
ISBN 10: 084933778X
ISBN 13: 9780849337789
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Librería: Ground Zero Books, Ltd., Silver Spring, MD, Estados Unidos de America
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Hardcover. Condición: Very good. xxiii, [1], 2270, [2] pages. Signed by contributor Michael R. Landauer on fep. Minor page creasing. Dr. Landauer was a co-author of chapter 18. Dr. Hayes is a toxicologist with over 35 years of experience in industry and academics. He is a Senior Science Advisor at Spherix Consulting, providing strategic, scientific and regulatory guidance. Dr. Hayes also holds appointments at the Harvard School of Public Health and with the School of Public Health, University of Massachusetts. Dr. Hayes was the Corporate Toxicologist for RJR Nabisco with responsibility for all regulatory and toxicology issues related to the safety of ingredients and food contact substances for food and drink products. Corporate Vice-President of Product Integrity at the Gillette Company, he had responsibility for the safety evaluation and regulatory compliance of a variety of consumer products, plant safety, environmental stewardship, and quality control. At Gillette, he was responsible for managing regulatory and toxicology issues worldwide. Extensively revised and updated with new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. Each method or procedure is examined from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a more diverse treatment of the expanding field of toxicology. Maintaining the high-quality information and organizational framework, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology. Fifth Edition [stated]. First printing [stated]. Nº de ref. del artículo: 74391
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Principles and Methods of Toxicology, Fifth Edition
Librería: GoldBooks, Denver, CO, Estados Unidos de America
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