The fourth edition of Ghadially's Ultrastructural Pathology of the Cell and Matrix is as beautiful as its three predecessors.......If you do not yet own 'a Ghadially', this edition will grace bookshelves as well as any of the previous ones.
For all those skeptics who have been predicting the demise of electron microscopy for years, Dr. Ghadially has prepared a surprise by updating his book and showing beyond reasonable doubt that 'yet we have not seen it all'...The present two-volume compendium and atlas is the best testimonial to that end....In the fourth edition, the author has thoroughly updated the previous edition and added new pictures, new references, new interpretations, and even new chapters..... There are few academicians who, as they say, have had the talent to generate the spark and transmit the fire. Dr. Ghadially has been one of those giants who has done original research and prepared materials for transmittal to the future generations. His book remains essential reading for all those entering the field, but it is also indispensable to all those who use electron microscopy for either research or diagnosis. I should add also that for those who use electron microscopy for teaching it is still one of the best ways to teach students to see through the ordinary light microscope.
Ghadially successfully collects, classifies, describes, and illustrates the ultrastructure of every normal and pathological intracellular and extracellular structure in humans and other animals.
This authoritative work serves as a textbook and atlas of cellular pathology at the ultrastructural level. There is no other book from which one may learn in a systemic fashion about the numerous changes that occur in cellular organelles and inclusions as a result of disease or experimental procedures. The 4th edition includes a number of new ultrastructural changes and lesions such as, secretory granules in bronchio-alveolar carcinoma, fibrohistiocytes, crinophagy in normal and neoplastic cells, and interdigitations and infoldings of the cell membrane.
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