Molecular Oncology: Causes of Cancer and Targets for Treatment

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9780521876629: Molecular Oncology: Causes of Cancer and Targets for Treatment

The genomic era has greatly facilitated the understanding of the molecular changes that underlie malignant transformation. This timely foundation for understanding the origins of molecular oncology reviews available technologies for cancer analysis, summaries of key oncogenic pathways for a wide range of human malignancies, and pharmacologic therapies in development.

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Reseña del editor:

The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target.

Biografía del autor:

Edward P. Gelmann is Chief of the Division of Hematology/Oncology and Deputy Director for Clinical Research at the Herbert Irving Comprehensive Cancer Center and Columbia University Medical Center, New York, NY, USA.

Charles L. Sawyers is Chair of the Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

Frank J. Rauscher III is Professor of the Gene Expression and Regulation Program, Professor of the Tumor Microenvironment and Metastasis Program, and Deputy Director for Basic Research at the Wistar Institute Cancer Center, Philadelphia, PA, USA.

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Editorial: Cambridge University Press (2014)
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Gelmann, Edward P.
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Descripción CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 2014. Hardback. Estado de conservación: New. 278 x 226 mm. Language: English . Brand New Book. The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target. Nº de ref. de la librería AAC9780521876629

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Editorial: CAMBRIDGE UNIVERSITY PRESS, United Kingdom (2014)
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Descripción CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 2014. Hardback. Estado de conservación: New. 278 x 226 mm. Language: English . Brand New Book. The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target. Nº de ref. de la librería AAC9780521876629

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Editorial: CAMBRIDGE UNIVERSITY PRESS, United Kingdom (2014)
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Descripción CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 2014. Hardback. Estado de conservación: New. 278 x 226 mm. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target. Nº de ref. de la librería BTE9780521876629

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Gelmann, Edward P. [Editor]; Sawyers MD, Charles L. [Editor]; Rauscher III, Frank J. [Editor];
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Edward P. Gelmann, Charles L. Sawyers MD, Frank J. Rauscher III
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Edward P. Gelmann (editor), Charles L. Sawyers (editor), Frank J. Rauscher, III (editor)
Editorial: Cambridge University Press 2013-12-19, Cambridge (2013)
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