"Without question LC/MS is the most dominant application of mass spectrometry in the pharmaceutical industry ... That being said, the editors should be commended for how well they took on such a comprehensive subject and worked with several recognized contributors to make a text that is both manageable and highly informative." (J Am Soc Mass Spectrom, 2007) "...extremely useful and quite extensive in its coverage of the subject..." (Journal of the American Chemical Society, July 18, 2007)From the Publisher:
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
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