Synthetic Multivalent Molecules: Concepts and Biomedical Applications

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9780471563471: Synthetic Multivalent Molecules: Concepts and Biomedical Applications

This book provides basic principles of multivalent interactions found in biological systems as well as an up-to-date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules.
* Contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine
* Can be used as both a textbook for students and a reference book for libraries and professionals
* Includes detailed case studies
* Fills a void in current literature through its devotion solely to multivalent molecules

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From the Back Cover:

The first reference devoted solely to multivalent molecules

Interest in multivalent molecules has recently increased due to the biomedical applications of multivalent interaction. This interaction, analogous to the process of a zipper closing, occurs with receptor contact at multiple binding sites simultaneously. While conventional drugs are monovalent, a new class of multivalent drugs has the potential to treat a broad range of diseases with improved safety, efficacy, potency, and duration of action.

Synthetic Multivalent Molecules: Concepts and Biomedical Applications presents both the basic principles of multivalent interactions and up-to-date coverage of the design concepts, synthesis, and biological activity of multivalent molecules. With a systematic summary of experimentally tested case studies, this clearly written text serves to bring together otherwise scattered research material. Chapters cover multivalent molecules in the context of:

  • Definition and structural elements
  • Mechanistic basis of interaction
  • Biological functions
  • Biological targets in viruses, bacteria, and mammalian cells
  • Methods for synthesis of multivalent molecules

Synthetic Multivalent Molecules functions admirably as both a textbook for students and a reference for libraries and professionals. Special features include more than 300 figures and illustrations that show multivalent concepts, molecular design, and chemical synthesis; summaries of all examples in tabular form in an appendix; and an extensive bibliography referencing over 900 citations.

Intended for a broad community of audiences made up of educators, advanced students, and professional researchers in academia and industry, Synthetic Multivalent Molecules: Concepts and Biomedical Applications stands as an invaluable, state-of-the-art reference.

About the Author:

SEOK-KI CHOI works for Theravance, Inc., where he gained firsthand insight into the application of multivalent drug design and development. Prior to his work at Theravance, he served on the faculty in the Department of Chemistry and Chemical Biology at Harvard University, establishing his credentials in the field. He is a member of the American Chemical Society and has authored several papers and articles in the biochemistry field.

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Descripción John Wiley and Sons Ltd, United States, 2004. Hardback. Estado de conservación: New. New.. Language: English . Brand New Book. This book provides basic principles of multivalent interactions found in biological systems as well as an up to date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. It contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine. It can be used as both a textbook for students and a reference book for libraries and professionals. It includes detailed case studies and fills a void in current literature through its devotion solely to multivalent molecules. Nº de ref. de la librería AAH9780471563471

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Descripción Wileyand#8211;Blackwell, 2004. HRD. Estado de conservación: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Nº de ref. de la librería FW-9780471563471

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Descripción John Wiley and Sons Ltd, United States, 2004. Hardback. Estado de conservación: New. New.. Language: English . Brand New Book. This book provides basic principles of multivalent interactions found in biological systems as well as an up to date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. It contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine. It can be used as both a textbook for students and a reference book for libraries and professionals. It includes detailed case studies and fills a void in current literature through its devotion solely to multivalent molecules. Nº de ref. de la librería AAH9780471563471

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Descripción John Wiley and Sons Ltd. Hardback. Estado de conservación: new. BRAND NEW, Synthetic Multivalent Molecules: Concepts and Biomedical Applications, Seok-ki Choi, This book provides basic principles of multivalent interactions found in biological systems as well as an up to date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. It contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine. It can be used as both a textbook for students and a reference book for libraries and professionals. It includes detailed case studies and fills a void in current literature through its devotion solely to multivalent molecules. Nº de ref. de la librería B9780471563471

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Descripción John Wiley and Sons Ltd, United States, 2004. Hardback. Estado de conservación: New. New.. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. This book provides basic principles of multivalent interactions found in biological systems as well as an up to date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. It contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine. It can be used as both a textbook for students and a reference book for libraries and professionals. It includes detailed case studies and fills a void in current literature through its devotion solely to multivalent molecules. Nº de ref. de la librería BZV9780471563471

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Descripción Wiley-Interscience, 2004. Hardcover. Estado de conservación: Brand New. 1st edition. 418 pages. 9.25x6.25x1.00 inches. In Stock. Nº de ref. de la librería __0471563471

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