Genomics, Proteomics and Vaccines

ISBN 13: 9780470856161

Genomics, Proteomics and Vaccines

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9780470856161: Genomics, Proteomics and Vaccines

While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly.

Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens.

This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions

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From the Back Cover:

The field of vaccine development is one of the first to benefit from the new technologies of genomics, proteomics and bioinformatics. The complete genome sequences of many bacteria are available and comparisons of pathogenic strains with non-pathogenic relatives are becoming common. Vaccines can now be targeted towards specific gene products that traditional vaccine research failed to discover. This book describes the current status of this field and summarizes the various strategies that are delivering results.

The introductory section provides an overview of vaccine research and looks at how genomics can complement traditional approaches. The second section focuses on advanced technologies, such as genome sequence analysis, microarrays, proteomics and high-throughput cloning.

The third section constitutes the unique part of this book, with six chapters that describe the application of genomic and proteomic techniques in the search for new antibacterial vaccines. The target pathogens include meningococcus B, streptococci, chlamydia and Pseudomonas.

Infectious diseases are once again threatening the health of human populations, even in countries where they were thought to have been controlled. With the spread of antibiotic resistance, the concept of prevention rather than cure becomes ever more important. The new genomic approaches described in this book will help to accelerate vaccine development and benefit the health of millions of people worldwide.

This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions.

Review:

"...this book kept me fascinated for many hours...it is an excellent book..." (Journal of Chemical Technology & Biotechnology, Vol 80 (11), November 2005)

"...an excellent book on a topical issue that will appeal to research scientists looking to find new and alternative means of designing and developing vaccines." (ASM News, March 2005)

"...chapters are written by experts in the field...new data is provided as well as descriptions of their biology..." (CAB Publishing, 2004)

"...should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions." (The Biotech Journal, November/December 2003)

"Sobre este título" puede pertenecer a otra edición de este libro.

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Editorial: Wiley (2004)
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Descripción John Wiley and Sons Ltd, United Kingdom, 2004. Hardback. Estado de conservación: New. New.. Language: English . Brand New Book. While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions. Nº de ref. de la librería AAH9780470856161

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Descripción John Wiley and Sons Ltd, United Kingdom, 2004. Hardback. Estado de conservación: New. New.. Language: English . Brand New Book. While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions. Nº de ref. de la librería AAH9780470856161

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