James C. Dabrowiak Metals in Medicine

ISBN 13: 9780470681961

Metals in Medicine

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9780470681961: Metals in Medicine

Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, Feature Boxes expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medi

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In recent years the field of medicinal inorganic chemistry has extended far beyond the traditional areas of platinum anticancer drugs. As metal-based drugs become increasingly common in the drug market, an understanding of medicinal inorganic chemistry is essential for successful drug design and development.

Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents.

Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, examining their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include:

  • cisplatin and other platinum anticancer drugs
  • ruthenium, titanium, and gallium for treating cancer
  • gold compounds for treating arthritis, cancer, and other diseases
  • vanadium, copper, and zinc in medicine
  • metal complexes for diagnosing disease
  • the emerging field of metals in nanomedicine.

Throughout the book, Feature Boxes expand on related topics such as drug discovery, synthesis and principles behind medical techniques. Following each chapter there are specifically designed exercises, with solutions, that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in the topic being addressed.

Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology and bioengineering.

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1.

James C. Dabrowiak
Editorial: John Wiley and Sons Ltd, United States (2010)
ISBN 10: 0470681969 ISBN 13: 9780470681961
Nuevos Tapa dura Cantidad: 1
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The Book Depository US
(London, Reino Unido)
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Descripción John Wiley and Sons Ltd, United States, 2010. Hardback. Estado de conservación: New. 252 x 192 mm. Language: English . Brand New Book. Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, Feature Boxes expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medicine. Nº de ref. de la librería AAH9780470681961

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2.

James C. Dabrowiak
Editorial: John Wiley and Sons Ltd, United States (2010)
ISBN 10: 0470681969 ISBN 13: 9780470681961
Nuevos Tapa dura Cantidad: 1
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The Book Depository
(London, Reino Unido)
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Descripción John Wiley and Sons Ltd, United States, 2010. Hardback. Estado de conservación: New. 252 x 192 mm. Language: English . Brand New Book. Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, Feature Boxes expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medicine. Nº de ref. de la librería AAH9780470681961

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James C. Dabrowiak
Editorial: Wileyand#8211;Blackwell (2009)
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción Wileyand#8211;Blackwell, 2009. HRD. Estado de conservación: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Nº de ref. de la librería FW-9780470681961

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James C. Dabrowiak (Syracuse University, USA)
Editorial: John Wiley and Sons
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción John Wiley and Sons. Estado de conservación: New. Brand New. Nº de ref. de la librería 0470681969

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Dabrowiak, James C.
Editorial: Wiley (2009)
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción Wiley, 2009. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería 0470681969

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James C. Dabrowiak
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción 2009. Hardcover. Estado de conservación: New. 1st. 197mm x 255mm x 23mm. Hardcover. Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 334 pages. 0.812. Nº de ref. de la librería 9780470681961

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JAMES C. DABROWIAK
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción 2009. Hardback. Estado de conservación: NEW. 9780470681961 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE0773617

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Dabrowiak, James C.
Editorial: John Wiley & Sons Inc (2010)
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción John Wiley & Sons Inc, 2010. Hardcover. Estado de conservación: Brand New. 1st edition. 334 pages. 10.00x7.75x1.00 inches. In Stock. Nº de ref. de la librería __0470681969

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James C. Dabrowiak
Editorial: Wiley-Blackwell (2009)
ISBN 10: 0470681969 ISBN 13: 9780470681961
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Descripción Wiley-Blackwell, 2009. Hardcover. Estado de conservación: New. 19.7 x 25.5 cm. Our orders are sent from our warehouse locally or directly from our international distributors to allow us to offer you the best possible price and delivery time. Book. Nº de ref. de la librería MM-60132718

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