Glutathione and Sulfur Amino Acids in Human Health and Disease

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9780470170854: Glutathione and Sulfur Amino Acids in Human Health and Disease

The complex roles of glutathione and sulfur amino acids in human health

Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids.

The twenty-two chapters explore such topics as:

  • Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids
  • Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses
  • Biological activities of GSH and sulfur amino acids and their role in modulating cell processes
  • Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging
  • Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals

Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models.

With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.

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Glutathione and Sulfur Amino Acids in Human Health and Disease

Edited by Roberta Masella and Giuseppe Mazza

About the Author:

Roberta Masella works as Head of the Human Nutrition Unit, Department of Veterinary Public Health and Food Safety, at Istituto Superiore di Sanità (ISS). She was previously head of the Gastroenterology Unit in the Laboratory of Metabolism and Pathological Biochemistry at ISS. She is the author of nearly 100 peer-reviewed publications, as well as seventy presentations at international congresses.

Giuseppe (Joe) Mazza is the Principal Food and Bioscience Research Scientist at Agriculture and Agri-Food Canada, Summerland, British Columbia, and an adjunct professor in food science and nutrition at the Universities of Manitoba and British Columbia. A prolific author and editor of over 200 journal articles and twelve books, he is on the editorial boards of World of Food Science, Plant Foods for Human Nutrition, Italian Journal of Food Science, and Journal of Functional Foods.

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Roberta Masella, Giuseppe Mazza
Editorial: John Wiley and Sons Ltd, United States (2009)
ISBN 10: 0470170859 ISBN 13: 9780470170854
Nuevos Tapa dura Primera edición Cantidad: 1
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Descripción John Wiley and Sons Ltd, United States, 2009. Hardback. Estado de conservación: New. 1. Auflage. Language: English . Brand New Book. This book gives researchers and their associates a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. Discussion deals with the complex relationship between GSH and sulfur amino acids and their physiological role, as well as they and their metabolites possible role in chronic-degenerative diseases. Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities. Finally, the book covers the nutritional and therapeutic significance of dietary sulfur amino acids, as shown in human and animal models. Nº de ref. de la librería AAH9780470170854

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Roberta Masella, Giuseppe Mazza
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ISBN 10: 0470170859 ISBN 13: 9780470170854
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Descripción Wiley 2009-07-17, Oxford, 2009. hardback. Estado de conservación: New. Nº de ref. de la librería 9780470170854

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Roberta Masella, Giuseppe Mazza
Editorial: John Wiley and Sons Ltd, United States (2009)
ISBN 10: 0470170859 ISBN 13: 9780470170854
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Descripción John Wiley and Sons Ltd, United States, 2009. Hardback. Estado de conservación: New. 1. Auflage. Language: English . Brand New Book. This book gives researchers and their associates a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. Discussion deals with the complex relationship between GSH and sulfur amino acids and their physiological role, as well as they and their metabolites possible role in chronic-degenerative diseases. Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities. Finally, the book covers the nutritional and therapeutic significance of dietary sulfur amino acids, as shown in human and animal models. Nº de ref. de la librería AAH9780470170854

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Roberta Masella; Giuseppe Mazza
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Descripción Wiley, 2009. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería M0470170859

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Descripción John Wiley & Sons Inc, 2009. Hardcover. Estado de conservación: Brand New. 1st edition. 598 pages. 9.50x6.25x1.50 inches. In Stock. Nº de ref. de la librería __0470170859

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