NMR and Chemistry: An Introduction to Modern NMR Spectroscopy - Tapa dura

This new edition of a successful text has been thoroughly revised to provide an introduction to current high resolution NMR practice. It is aimed at both undergraduate and graduate students. As in earlier editions it starts with a simple introduction to nuclear properties, nuclear screening, chemical shift and spin-spin coupling phenomena. The relaxation of nuclei is described and the use of such data for determining details of molecular motion is discussed with attention given to the significance of quadrupole relaxation. The requirements for a modern spectrometer system are also described. Considerably more space than was given in the earlier editions is devoted to the effects of exchange on NMR spectra and how changes or rates of reaction with either temperature or pressure, may be monitored. Double resonance and nuclear Overhauser effects are described and the way these can be used to interpret spectra or to obtain spatial structural information are discussed, though it is pointed out that much double resonance work has been superseded by the new two-dimensional techniques. The INEPT and DEPT experiments are also described. The following chapter is devoted to two-dimensional methods and uses a study of the relatively simple molecule D-amygdalin techniques. NMR Imaging is discussed briefly, both its medical uses and the more recent technological and micro-imaging techniques. Finally, high resolution solid state spectroscopy is discussed, dealing in turn with spin half nuclei, quadrupolar nuclei with half integral spin and deuterium.