The US Environmental Protection Agency asked the Council to review the methods and strategies currently being used to evaluate the hazards of risks associated with exposure to drugs, food additives, pesticides, and industrial and other chemicals. The committee assigned to the task, having submitted an interim report in 2006, here presents its long-range vision and strategic plan to advance toxicity testing, and considers its vision within the current regulatory framework. No index is provided. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
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Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Committee on Toxicity Testing and Assessment of Environmental Agents, National Research Council
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