Junk DNA: A Journey Through the Dark Matter of the Genome

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9780231170840: Junk DNA: A Journey Through the Dark Matter of the Genome

For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions.

Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field.

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Book Description:

From the author of The Epigenetics Revolution ("A book that would have had Darwin swooning."-- Guardian) comes a lucid and engaging report from the cutting edge of genomic biology.

About the Author:

Nessa Carey is a visiting professor at Imperial College, London. She earned her Ph.D. in virology from the University of Edinburgh. Having worked in the biotech and pharmaceutical industries for more than a decade, she maintains strong relationships with leading researchers in Europe and across the United States, at such institutions as the Harvard Medical School, the University of Pennsylvania, the Wistar Institute, the MD Anderson Cancer Center, and the University of Southern California. Carey is also the author of The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance.

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Carey, Nessa
Editorial: Columbia Univ Pr (2015)
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Descripción Columbia Univ Pr, 2015. HRD. Estado de conservación: New. New Book.Shipped from US within 10 to 14 business days. Established seller since 2000. Nº de ref. de la librería IB-9780231170840

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Descripción Columbia Univ Pr, 2015. HRD. Estado de conservación: New. New Book. Shipped from US within 10 to 14 business days. Established seller since 2000. Nº de ref. de la librería KB-9780231170840

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Descripción Columbia University Press 4/14/2015, 2015. Hardback or Cased Book. Estado de conservación: New. Junk DNA: A Journey Through the Dark Matter of the Genome. Book. Nº de ref. de la librería BBS-9780231170840

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Descripción Columbia University Press, 2015. Hardcover. Estado de conservación: New. Never used!. Nº de ref. de la librería 023117084X

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Descripción Columbia University Press, United States, 2015. Hardback. Estado de conservación: New. Language: English . Brand New Book. For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as junk, sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word gene and have engendered a spirited scientific battle over whether or not this genomic nonsense is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey s book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. Nº de ref. de la librería AAS9780231170840

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Nessa Carey
Editorial: Columbia University Press, United States (2015)
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Descripción Columbia University Press, United States, 2015. Hardback. Estado de conservación: New. Language: English . Brand New Book. For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as junk, sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word gene and have engendered a spirited scientific battle over whether or not this genomic nonsense is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey s book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. Nº de ref. de la librería AAS9780231170840

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Descripción Columbia University Press. Hardcover. Estado de conservación: New. 023117084X Brand New! Not Overstocks or Low Quality Book Club Editions! Direct From the Publisher! We're not a giant, faceless warehouse organization! We're a small town bookstore that loves books and loves it's customers! Buy from us and you get great service as well as a great price! Your business is valued and your satisfaction is guaranteed!. Nº de ref. de la librería OTF-S-9780231170840

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Descripción Hardcover. Estado de conservación: New. Hardcover. For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions t.Shipping may be from multiple locations in the US or from the UK, depending on stock availability. 360 pages. 0.454. Nº de ref. de la librería 9780231170840

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Descripción Columbia University Press. Hardcover. Estado de conservación: New. Hardcover. 360 pages. For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 of the human genome were dismissed as junk, sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word gene and has engendered a bitter battle over whether or not this genomic nonsense is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Careys book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Hardcover. Nº de ref. de la librería 9780231170840

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Descripción Columbia University Press, United States, 2015. Hardcover. Estado de conservación: New. HARDCOVER Legendary independent bookstore online since 1994. Reliable customer service and no-hassle return policy. Science and Mathematics>Biology>General. Book: NEW, New. Bookseller Inventory # 01978023117084000. Nº de ref. de la librería 01978023117084000

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