Studies of evolution at the molecular level have experienced phenomenal growth in the last few decades, due to rapid accumulation of genetic sequence data, improved computer hardware and software, and the development of sophisticated analytical methods. The flood of genomic data has generated an acute need for powerful statistical methods and efficient computational algorithms to enable their effective analysis and interpretation.
Molecular Evolution: a statistical approach presents and explains modern statistical methods and computational algorithms for the comparative analysis of genetic sequence data in the fields of molecular evolution, molecular phylogenetics, statistical phylogeography, and comparative genomics. Written by an expert in the field, the book emphasizes conceptual understanding rather than mathematical proofs. The text is enlivened with numerous examples of real data analysis and numerical calculations to illustrate the theory, in addition to the working problems at the end of each chapter. The coverage of maximum likelihood and Bayesian methods are in particular up-to-date, comprehensive, and authoritative.
This advanced textbook is aimed at graduate level students and professional researchers (both empiricists and theoreticians) in the fields of bioinformatics and computational biology, statistical genomics, evolutionary biology, molecular systematics, and population genetics. It will also be of relevance and use to a wider audience of applied statisticians, mathematicians, and computer scientists working in computational biology.
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Ziheng Yang, RA Fisher Professor of Statistical Genetics, Department of Genetics, Evolution and Environment, University College London
Ziheng Yang is currently RA Fisher Professor of Statistical Genetics in University College London. He obtained a Ph. D in agronomy in Beijing Agricultural University in 1992. Since then he held a few postdoctoral researcher positions in the UK and US. He joined UCL in 1997, first as a lecturer, then reader and professor. He teaches statistical genetics. He has published about 150 research papers and book chapters in molecular evolution, phylogenetics, population genetics, and computational biology. His program package paml is widely used in the molecular evolution community. He was elected a Fellow of the Royal Society in 2006.
"The book gives a lot of mathematical insight while retaining readability. ... Yang has a talent for making general statistical concepts come to life in a very readable way." --Systematic Biology
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Descripción OUP Oxford 2014-05-15, Oxford, 2014. hardback. Estado de conservación: New. Nº de ref. de la librería 9780199602605
Descripción Oxford Univ Pr, 2014. Hardcover. Estado de conservación: Brand New. 1st edition. 512 pages. 9.75x7.75x1.50 inches. In Stock. Nº de ref. de la librería zk0199602603
Descripción Oxford University Press, 2014. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería M0199602603
Descripción Oxford University Press, 2014. Hardcover. Estado de conservación: New. Never used!. Nº de ref. de la librería P110199602603