The squid giant synapse is the single most important model for investigating the transmitter release mechanism in chemical junctions. This unique book, by a leading expert in the field, gives a concise overview of all that has been learned about synaptic transmission in this superb model system. It covers in detail the biophysics of the voltage-dependent calcium currents, calcium concentration microdomains, and much of the molecular basis for the triggering of the secretory event. Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission. One program is a modeling tool designed for working neuroscientists, and the other teaches the basic principles of synaptic transmission by allowing students to alter the parameters, essentially without limits, and see the effects on the action potential over time. Anyone studying this central topic of neuroscience will find this book an invaluable resource.
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Rodolfo R. Llinas, Thomas and Suzanne Murphy Professor of Neuroscience and Chair of the Department of Physiology and Neuroscience, New York University School of Medicine.Review:
"Given that the brain consists of some 100 billion nerve cells, understanding how synapses allow these cells to communicate with each other has been a core question in neuroscience. The past 50 years have seen remarkable advances in this area, largely due to a small number of experimental systems--such as neuromuscular synapses and the squid giant synapse--whose great advantages for physiological analyses have illuminated the beauty of synaptic function. Thus a book, such as The Squid Giant Synapse, that concisely highlights the contributions of one such model system is a very good idea. An even better idea is to have the book written by Rodolfo Llinás, a distinguished synaptic physiologist . . . Llinás has done a good job of capturing the excitement that has kept the field of synaptic physiology energized. By its example, he Squid Giant Synapse offers a strong argument for the continued value of physiological analyses of brain function, even in these genomic times."--Science
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Descripción Oxford University Press. Hardcover. Estado de conservación: New. 0195116526 New Condition. Nº de ref. de la librería NEW7.0974704
Descripción Oxford University Press, 1999. Hardcover. Estado de conservación: New. Nº de ref. de la librería P110195116526
Descripción Oxford University Press, USA, 1999. Hardcover. Estado de conservación: New. 1. Nº de ref. de la librería DADAX0195116526
Descripción Oxford University Press, 1999. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería M0195116526
Descripción Oxford University Press, USA 1999-12-15, 1999. Hardcover. Estado de conservación: New. 1. 0195116526. Nº de ref. de la librería 513790
Descripción Dec 15, 1999. Estado de conservación: New. BEST BUY.CLEAN.OFX/DD. Nº de ref. de la librería 801174